SCHEMBL14129702

SCHEMBL14129702

CCCCCC(NC(=O)C(Cc1ccccc1)NC(=O)COCC(=O)NCCOCCOCCN=[N+]=[N-])C(=O)Nc1ccc(CO)cc1

nearest known ligand 0.42

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
▸ CPA1 P15085 1/20 0.42
▸ CPA2 P48052 1/20 0.42
▸ CPA4 Q9UI42 1/20 0.42
▸ SSTR3 P32745 1/20 0.41
▸ CCKAR P32238 5/20 0.40
▸ CCKBR P32239 5/20 0.40
▸ SIRT2 Q8IXJ6 5/20 0.40
▸ SIRT1 Q96EB6 3/20 0.40
▸ SIRT3 Q9NTG7 3/20 0.40
▸ FOLH1 Q04609 1/20 0.40
▸ CTSL P07711 1/20 0.39
▸ GLP1R P43220 5/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14129704 0.85 SSTR3 (0.48) CPA1CPA2CPA4SSTR3CCKAR
SCHEMBL26015579 0.84 ITGB1 (0.43) FOLH1
SCHEMBL31681443 0.83 SIRT1 (0.37) CPA1CPA2CPA4SIRT2SIRT1
SCHEMBL15928006 0.81 SSTR3 (0.44) SSTR3SIRT2SIRT1
SCHEMBL25242024 0.81 FOLH1 (0.37) SIRT2SIRT1FOLH1
SCHEMBL25242026 0.81 FOLH1 (0.37) SIRT2SIRT1FOLH1
SCHEMBL26024621 0.81 FOLH1 (0.41) FOLH1
SCHEMBL19732156 0.80 FOLH1 (0.37) SIRT2SIRT1FOLH1
SCHEMBL22618772 0.79 FURIN (0.40) SIRT2SIRT1
SCHEMBL22618827 0.79 C3AR1 (0.41) SIRT2SIRT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8067006-B2 Polymeric carriers of therapeutic agents and recognition moieties for antibody-based targeting of disease sites IMMUNOMEDICS, INC. (US) 2011-11-29 — — US disclosed
US-20100233779-A1 Polymeric Carriers of Therapeutic Agents and Recognition Moieties for Antibody-Based Targeting of Disease Sites IMMUNOMEDICS, INC. (US) 2010-09-16 — — US disclosed
US-20080171067-A1 Polymeric Carriers of Therapeutic Agents and Recognition Moieties for Antibody-Based Targeting of Disease Sites IMMUNOMEDICS, INC. (US) 2008-07-17 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080171067-A1 Polymeric Carriers of Therapeutic Agents and Recognition Moieties for Antibody-Based Targeting of Disease Sites CD47, BSG, SELPLG CPA1 1468/4885CPA2 1743/4885CPA4 1762/4885
US-20100233779-A1 Polymeric Carriers of Therapeutic Agents and Recognition Moieties for Antibody-Based Targeting of Disease Sites CD47, BSG, SELPLG CPA1 1468/4885CPA2 1743/4885CPA4 1762/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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