Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR3 | P32745 | 1/20 | 0.44 |
| ▸ | CALCRL | Q16602 | 2/20 | 0.42 |
| ▸ | TLR2 | O60603 | 1/20 | 0.39 |
| ▸ | CHRNA1 | P02708 | 2/20 | 0.38 |
| ▸ | CHRNG | P07510 | 2/20 | 0.38 |
| ▸ | CHRNB1 | P11230 | 2/20 | 0.38 |
| ▸ | CHRND | Q07001 | 2/20 | 0.38 |
| ▸ | MMP3 | P08254 | 1/20 | 0.38 |
| ▸ | PLG | P00747 | 1/20 | 0.38 |
| ▸ | SIRT5 | Q9NXA8 | 3/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.37 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.37 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.37 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.37 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.37 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.37 |
| ▸ | F2 | P00734 | 1/20 | 0.37 |
| ▸ | ECE1 | P42892 | 1/20 | 0.37 |
| ▸ | NPY1R | P25929 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14129702 | 0.81 | CPA1 (0.42) | SSTR3SIRT2SIRT1 | |
| SCHEMBL26015579 | 0.79 | ITGB1 (0.43) | CALCRL | |
| SCHEMBL25359743 | 0.79 | CALCRL (0.51) | SSTR3CALCRLCHRNA1CHRNGCHRNB1 | |
| SCHEMBL25363467 | 0.79 | CALCRL (0.51) | SSTR3CALCRLCHRNA1CHRNGCHRNB1 | |
| SCHEMBL26024621 | 0.78 | FOLH1 (0.41) | CALCRL | |
| SCHEMBL23286081 | 0.77 | SSTR3 (0.53) | SSTR3CALCRLMMP3SIRT5SIRT2 | |
| SCHEMBL16984908 | 0.75 | CALCRL (0.51) | SSTR3CALCRLCHRNA1CHRNGCHRNB1 | |
| SCHEMBL14015260 | 0.75 | SIRT2 (0.40) | MMP3SIRT5SIRT2SIRT1 | |
| SCHEMBL26015717 | 0.75 | HDAC3 (0.47) | ECE1NPY1R | |
| SCHEMBL16854865 | 0.75 | CALCRL (0.54) | SSTR3CALCRLCHRNA1CHRNGCHRNB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9226973-B2 | Dosages of immunoconjugates of antibodies and SN-38 for improved efficacy and decreased toxicity | IMMUNOMEDICS, INC. (US) | 2016-01-05 | — | — | US | disclosed |
| US-20140219914-A1 | Dosages of Immunoconjugates of Antibodies and SN-38 for Improved Efficacy and Decreased Toxicity | IMMUNOMEDICS, INC. (US) | 2014-08-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140219914-A1 | Dosages of Immunoconjugates of Antibodies and SN-38 for Improved Efficacy and Decreased Toxicity | CD74, CD2, CD22 | SSTR3 942/4885CALCRL 2838/4885TLR2 1487/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.