Sugi Predict

Sugi Predict / Compounds / SCHEMBL141303

SCHEMBL141303

SCHEMBL141303

O=[N+]([O-])c1ccc2c(c1)OCO2

nearest known ligand 0.71

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 7/20 0.59
▸ RAB9A P51151 5/20 0.57
▸ NPC1 O15118 3/20 0.57
▸ MTOR P42345 1/20 0.57
▸ VCP P55072 1/20 0.57
▸ ALDH1A1 P00352 3/20 0.56
▸ SMN1; SMN2 Q16637 2/20 0.56
▸ MEN1 O00255 4/20 0.56
▸ KMT2A Q03164 4/20 0.56
▸ GAA P10253 1/20 0.56
▸ PTPN1 P18031 1/20 0.55
▸ HTT P42858 1/20 0.55
▸ LMNA P02545 1/20 0.54
▸ SETD7 Q8WTS6 1/20 0.54
▸ TLR9 Q9NR96 1/20 0.52
▸ L3MBTL1 Q9Y468 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30448936 1.00 MAPT (0.59) MAPTRAB9ANPC1MTORVCP
Formaldehyde SCHEMBL27922643 0.96 MAPT (0.56) MAPTRAB9ANPC1MTORVCP
SCHEMBL1169369 0.88 MAPT (0.60) MAPTRAB9ANPC1ALDH1A1SMN1; SMN2
SCHEMBL30665998 0.88 MAPT (0.60) MAPTRAB9ANPC1ALDH1A1SMN1; SMN2
SCHEMBL10845095 0.85 MEN1 (0.54) MAPTRAB9ANPC1ALDH1A1SMN1; SMN2
SCHEMBL789047 0.85 MAPT (0.47) MAPTRAB9ANPC1ALDH1A1SMN1; SMN2
SCHEMBL14849221 0.83 MAPT (0.56) MAPTRAB9ANPC1ALDH1A1SMN1; SMN2
SCHEMBL31710622 0.83 RAB9A (0.49) MAPTRAB9ANPC1MTORVCP
SCHEMBL20774271 0.83 MAPT (0.56) MAPTRAB9ANPC1ALDH1A1SMN1; SMN2
SCHEMBL31474894 0.83 MAPT (0.56) MAPTRAB9ANPC1ALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 280 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240294496-A1 PRODUCTION METHOD FOR SYNTHETIC INTERMEDIATE OF MONOCYCLIC PYRIDINE DERIVATIVE EISAI R&D MANAGEMENT CO., LTD. (JP) 2024-09-05 — — US claimed
EP-4361139-A1 PRODUCTION METHOD FOR SYNTHETIC INTERMEDIATE OF MONOCYCLIC PYRIDINE DERIVATIVE Eisai R&D Management Co., Ltd. (JP) 2024-05-01 — — EP claimed
CN-117677613-A Process for producing synthetic intermediate of monocyclic pyridine derivative 卫材R&D管理有限公司 2024-03-08 — — CN claimed
CN-117645544-A Preparation method of 2-decyloxy-4-nitrophenol 江苏思达药业有限公司 2024-03-05 — — CN claimed
WO-2023032872-A1 PRODUCTION METHOD FOR SYNTHETIC INTERMEDIATE OF MONOCYCLIC PYRIDINE DERIVATIVE エーザイ・アール・アンド・ディー・マネジメント株式会社 2023-03-09 — — WO claimed
CN-104628910-B Catalyst for producing polypropylene with high isotacticity and preparation method thereof 中国石油天然气股份有限公司 2017-02-08 — — CN claimed
EP-0589952-B1 USE OF SUPLHUR METAAMINOPHENOLS FOR DYEING KERATINIC FIBRES, TINCTORIAL COMPOSITIONS AND NOVEL COMPOUNDS OREAL (FR) 1997-08-27 — — EP claimed
EP-0589952-A1 USE OF SUPLHUROUS METAAMINOPHENOLS FOR DYING KERATINIC FIBRES, TINCTORIAL COMPOSITIONS AND NOVEL COMPOUNDS. OREAL (FR) 1994-04-06 — — EP claimed
WO-1992022525-A1 USE OF SUPLHUROUS METAAMINOPHENOLS FOR DYING KERATINIC FIBRES, TINCTORIAL COMPOSITIONS AND NOVEL COMPOUNDS L'OREAL (FR) 1992-12-23 — — WO claimed
US-4985042-A New substituted metaaminophenols, a process for their preparation, hair-dyeing compositions containing them and a hair-dyeing process L'OREAL (FR) 1991-01-15 — — US claimed
US-4973757-A Process for the preparation of nitroanilines L'OREAL (FR) 1990-11-27 — — US claimed
JP-5009160-A — — None — — JP disclosed
US-20260007760-A1 CAMPTOTHECIN DERIVATIVES THAT BIND TO DDX5 PROTEIN AND PRODRUGS THEREOF PINOTBIO, INC. (KR) 2026-01-08 — — US disclosed
US-20250327074-A1 THE RARE CODON RECODING PLATFORM FOR NONCANONICAL AMINO ACIDS INCORPORATION IN MAMMALIAN CELLS SHAOXING INSTITUTE, ZHEJIANG UNIVERSITY (CN) 2025-10-23 — — US disclosed
EP-4370593-B1 METHOD TO DEGRADE PLASTIC REPSOL SA (ES) 2025-09-10 — — EP disclosed
US-4058607-A DIHALOVINYL DIALKYL PHOSPHATE, 1,3-BENZODIOXOLES AIRWICK INDUSTRIES, INC. (US) 1977-11-15 — — US disclosed
US-3997564-A ANTIINFLAMMATORY SANDOZ, INC. (US) 1976-12-14 — — US disclosed
US-3978086-A INTERMEDIATES FOR 2-AMINO-4,5-METHYLENEDIOXYBENZOPHENONIMINES SANDOZ, INC. (US) 1976-08-31 — — US disclosed
US-3962415-A Insecticide evaporator comprising DDVP with synergized benzodioxole compound as stabilizer AIRWICK INDUSTRIES, INC. (US) 1976-06-08 — — US disclosed
US-3947434-A 9-(P-phenylazoanilino)-7-methyl-1H-imidazo[4,5-f]quinolines MORTON-NORWICH PRODUCTS, INC. (US) 1976-03-30 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240294496-A1 PRODUCTION METHOD FOR SYNTHETIC INTERMEDIATE OF MONOCYCLIC PYRIDINE DERIVATIVE FGFR1, FGFR2, FGFR3 MAPT 1821/4885RAB9A 592/4885NPC1 2854/4885
US-20260007760-A1 CAMPTOTHECIN DERIVATIVES THAT BIND TO DDX5 PROTEIN AND PRODRUGS THEREOF DDB1, DDX1, DDX18 MAPT 4511/4885RAB9A 3771/4885NPC1 4770/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.