Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.56 |
| ▸ | RAB9A | P51151 | 5/20 | 0.54 |
| ▸ | NPC1 | O15118 | 3/20 | 0.54 |
| ▸ | MTOR | P42345 | 1/20 | 0.54 |
| ▸ | VCP | P55072 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 4/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | SETD7 | Q8WTS6 | 1/20 | 0.51 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL141303 | 0.96 | MAPT (0.59) | MAPTRAB9ANPC1MTORVCP | |
| SCHEMBL30448936 | 0.96 | MAPT (0.59) | MAPTRAB9ANPC1MTORVCP | |
| SCHEMBL1169369 | 0.85 | MAPT (0.60) | MAPTRAB9ANPC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL30665998 | 0.85 | MAPT (0.60) | MAPTRAB9ANPC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL10845095 | 0.81 | MEN1 (0.54) | MAPTRAB9ANPC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL789047 | 0.81 | MAPT (0.47) | MAPTRAB9ANPC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL14849221 | 0.80 | MAPT (0.56) | MAPTRAB9ANPC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL31474894 | 0.80 | MAPT (0.56) | MAPTRAB9ANPC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL20774271 | 0.80 | MAPT (0.56) | MAPTRAB9ANPC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL31710622 | 0.80 | RAB9A (0.49) | MAPTRAB9ANPC1MTORVCP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103130705-B | Benzo five-membered unsaturated heterocycle compound or its pharmaceutical salts and preparation method thereof, pharmaceutical composition and application thereof | INSTITUTE OF MEDICINAL BIOTECHNOLOGY, CHINESE ACADEMY OF MEDICAL SCIENCES (CN) | 2016-04-20 | — | — | CN | disclosed |
| CN-103130705-A | Benzo five-membered unsaturated heterocyclic compound or pharmaceutically acceptable salt thereof, and preparation method, pharmaceutical composition and application thereof | INST MEDICINAL BIOTECHNOLOGY | 2013-06-05 | — | — | CN | disclosed |