Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2666923 | 0.96 | GCGR (0.62) | GCGR | |
| SCHEMBL14039369 | 0.93 | GCGR (0.58) | GCGR | |
| SCHEMBL14130852 | 0.90 | GCGR (0.57) | GCGRGCG | |
| SCHEMBL14130630 | 0.86 | GCGR (0.59) | GCGR | |
| SCHEMBL2667024 | 0.85 | GCGR (0.56) | GCGR | |
| SCHEMBL2666922 | 0.84 | GCGR (0.55) | GCGR | |
| SCHEMBL2666916 | 0.83 | TRPV1 (0.52) | GCGR | |
| SCHEMBL14039408 | 0.82 | GCGR (0.53) | GCGR | |
| SCHEMBL9071215 | 0.82 | GCGR (0.61) | GCGR | |
| SCHEMBL14130856 | 0.81 | GCGR (0.55) | GCGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080161347-A1 | Substituted Aryl and Heteroaryl Derivatives, Compositions Containing Such Compounds and Methods of Use | MERCK & CO., INC. (US) | 2008-07-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080161347-A1 | Substituted Aryl and Heteroaryl Derivatives, Compositions Containing Such Compounds and Methods of Use | GPR119, PNLIP, SLC5A2 | GCGR 81/4885GCG 135/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.