Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 1/20 | 0.45 |
| ▸ | SCD | O00767 | 9/20 | 0.41 |
| ▸ | GPR6 | P46095 | 3/20 | 0.41 |
| ▸ | DCK | P27707 | 2/20 | 0.40 |
| ▸ | RET | P07949 | 1/20 | 0.39 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14130929 | 0.88 | SCD (0.46) | SCN9ASCDGPR6DCKRET | |
| SCHEMBL3832548 | 0.84 | RET (0.42) | SCN9AGPR6DCKRETGRIN1 | |
| SCHEMBL3826351 | 0.84 | RET (0.42) | SCN9AGPR6DCKRETGRIN1 | |
| SCHEMBL3832527 | 0.82 | SCD (0.42) | SCDRET | |
| SCHEMBL3826339 | 0.81 | SCD (0.41) | SCDRET | |
| SCHEMBL3826490 | 0.80 | SCD (0.46) | SCN9ASCDGPR6DCK | |
| SCHEMBL14130918 | 0.80 | GRM5 (0.40) | SCDRET | |
| SCHEMBL3832526 | 0.77 | SCD (0.47) | SCN9ASCDDCK | |
| SCHEMBL14143841 | 0.74 | SCD (0.51) | SCN9ASCDGPR6DCKRET | |
| SCHEMBL3831479 | 0.72 | GRM5 (0.45) | SCDDCKRET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080182851-A1 | ACETYLENE DERIVATIVES AS STEAROYL COA DESATURASE INHIBITORS | GLENMARK PHARMACEUTICALS S.A. (CH) | 2008-07-31 | — | — | US | disclosed |
| US-20080182851-A1 | ACETYLENE DERIVATIVES AS STEAROYL COA DESATURASE INHIBITORS | GLENMARK PHARMACEUTICALS S.A. (CH) | 2008-07-31 | — | — | US | disclosed |
| WO-2008062276-A2 | ACETYLENE DERIVATIVES AS STEAROYL COA DESATURASE INHIBITORS | GLENMARK PHARMACEUTICALS S.A. (US) | 2008-05-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080182851-A1 | ACETYLENE DERIVATIVES AS STEAROYL COA DESATURASE INHIBITORS | SCD, SCD5, ACACA | SCN9A 2252/4885SCD 1/4885GPR6 2333/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.