SCHEMBL14130799

SCHEMBL14130799

C=CC(=O)Oc1ccc(C(=O)Oc2ccc(-c3ccccc3)cc2)cc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PARP10 Q53GL7 1/20 0.54
MAPT P10636 4/20 0.51
TDP1 Q9NUW8 4/20 0.51
KMT2A Q03164 6/20 0.50
MEN1 O00255 3/20 0.50
RAB9A P51151 1/20 0.49
ALDH1A1 P00352 2/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
PKM P14618 1/20 0.47
PDCD1 Q15116 1/20 0.46
CD274 Q9NZQ7 1/20 0.46
PDGFRB P09619 1/20 0.46
PDGFRA P16234 1/20 0.46
PRSS1 P07477 1/20 0.45
ACR P10323 1/20 0.45
TMPRSS15 P98073 1/20 0.45
PDE6D O43924 1/20 0.44
THRB P10828 1/20 0.44
KDM4E B2RXH2 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22566480 0.93 THRB (0.49) PARP10MAPTTDP1KMT2AMEN1
SCHEMBL22566606 0.93 THRB (0.49) PARP10MAPTTDP1KMT2AMEN1
SCHEMBL15695635 0.93 THRB (0.49) PARP10MAPTTDP1KMT2AMEN1
SCHEMBL21470125 0.93 THRB (0.49) PARP10MAPTTDP1KMT2AMEN1
SCHEMBL16429670 0.92 PARP10 (0.59) PARP10MAPTTDP1KMT2AMEN1
SCHEMBL27667566 0.92 PARP10 (0.59) PARP10MAPTTDP1KMT2AMEN1
SCHEMBL4908371 0.90 KMT2A (0.61) PARP10MAPTTDP1KMT2AMEN1
SCHEMBL8927324 0.90 THRB (0.51) MAPTTDP1KMT2AMEN1RAB9A
SCHEMBL819185 0.90 THRB (0.51) MAPTTDP1KMT2AMEN1RAB9A
SCHEMBL5710451 0.88 PARP10 (0.67) PARP10MAPTTDP1KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7396486-B2 Polymerizable mixtures WACKER CHEMIE AG (DE) 2008-07-08 US disclosed
US-7396486-B2 Polymerizable mixtures WACKER CHEMIE AG (DE) 2008-07-08 US disclosed