Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CG | P48736 | 1/20 | 0.56 |
| ▸ | BACE1 | P56817 | 1/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.47 |
| ▸ | SCN4A | P35499 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | PIM1 | P11309 | 1/20 | 0.41 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | NOS3 | P29474 | 1/20 | 0.39 |
| ▸ | NOS2 | P35228 | 1/20 | 0.39 |
| ▸ | LCK | P06239 | 1/20 | 0.39 |
| ▸ | KIF11 | P52732 | 1/20 | 0.38 |
| ▸ | IKBKB | O14920 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30238039 | 0.86 | LMNA (0.56) | PIK3CGBACE1EPHX2SCN4AMAPT | |
| SCHEMBL17267541 | 0.86 | LMNA (0.56) | PIK3CGBACE1EPHX2SCN4AMAPT | |
| SCHEMBL179511 | 0.82 | PIK3CG (0.56) | PIK3CGMAPTMAPK1LMNACYP1A2 | |
| SCHEMBL19914273 | 0.80 | ALDH1A1 (0.56) | BACE1EPHX2SCN4AMAPTKDM4E | |
| SCHEMBL18935939 | 0.79 | TLR9 (0.55) | MAPTKDM4EALDH1A1IKBKBMEN1 | |
| SCHEMBL18755165 | 0.79 | BACE1 (0.42) | BACE1EPHX2SCN4AKDM4EPIM1 | |
| SCHEMBL31208302 | 0.79 | BACE1 (0.42) | BACE1EPHX2SCN4AKDM4EPIM1 | |
| SCHEMBL12805011 | 0.79 | BACE1 (0.42) | PIK3CGBACE1EPHX2SCN4AKDM4E | |
| SCHEMBL2138359 | 0.78 | EPHX2 (0.44) | BACE1EPHX2SCN4AMAPTKDM4E | |
| SCHEMBL21389736 | 0.77 | PIK3CG (0.50) | PIK3CGMAPTMAPK1LMNACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10640476-B2 | Bicyclic heteroaryl derivatives and preparation and uses thereof | XW LABORATORIES INC. (KY) | 2020-05-05 | — | — | US | disclosed |
| WO-2011047323-A2 | ANTIMICROBIAL COMPOUNDS AND METHODS OF MAKING AND USING THE SAME | RIB-X PHARMACEUTICALS, INC. (US) | 2011-04-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10640476-B2 | Bicyclic heteroaryl derivatives and preparation and uses thereof | GRIN2A, GRIN2C, GRIN3A | PIK3CG 1975/4885BACE1 592/4885EPHX2 1013/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.