SCHEMBL14131007

SCHEMBL14131007

c1n[nH]cc1Cc1cn[nH]c1

nearest known ligand 0.64

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
NOS2 P35228 1/20 0.44
KCNH2 Q12809 1/20 0.43
LMNA P02545 1/20 0.42
APEX1 P27695 1/20 0.42
PMP22 Q01453 1/20 0.42
AKT2 P31751 2/20 0.37
AKT1 P31749 1/20 0.37
PDE4B Q07343 6/20 0.36
NTRK1 P04629 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2872833 0.86 CALM1 (0.52) AKT2AKT1
Hydrochloric Acid SCHEMBL23068338 0.84 CALM1 (0.50) AKT2AKT1
SCHEMBL9275163 0.84 ESR1 (0.58) NOS2
SCHEMBL23075432 0.84 HRH4 (0.46)
SCHEMBL3507535 0.82 KCNH2 (0.46) NOS2KCNH2LMNAAPEX1PMP22
SCHEMBL22968991 0.82 NTRK1 (0.42) PDE4BNTRK1
SCHEMBL31135323 0.82 CYP19A1 (0.49) AKT2AKT1PDE4B
Hydrochloric Acid SCHEMBL23067815 0.82 HRH4 (0.44)
SCHEMBL147944 0.82 METAP2 (0.42) NOS2KCNH2LMNAAPEX1PMP22
SCHEMBL28089823 0.82 NTRK1 (0.52) NOS2PDE4BNTRK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117843913-A Bipyrazole-based metal coordination self-repairing polyurethane elastomer and preparation method thereof 浙江大学 2024-04-09 CN disclosed
US-20080182834-A1 Multi-Nuclear Metal Complexes Partially Encapsulated by Cucurbit[7-12]Urils NEWSOUTH INNOVATIONS PTY LIMITED (AU) 2008-07-31 US disclosed
US-20080182834-A1 Multi-Nuclear Metal Complexes Partially Encapsulated by Cucurbit[7-12]Urils NEWSOUTH INNOVATIONS PTY LIMITED (AU) 2008-07-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080182834-A1 Multi-Nuclear Metal Complexes Partially Encapsulated by Cucurbit[7-12]Urils HNRNPUL2, HNRNPUL1, NUDC NOS2 1518/4885KCNH2 3334/4885LMNA 1984/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.