SCHEMBL14132017

SCHEMBL14132017

C=Cc1ccc(S(=O)(=O)OCC(C)(O)c2ccccc2)cc1

nearest known ligand 0.42

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 1/20 0.42
TDP1 Q9NUW8 1/20 0.41
ESR2 Q92731 6/20 0.40
ESR1 P03372 1/20 0.39
KMT2A Q03164 2/20 0.37
MCL1 Q07820 2/20 0.37
HSD11B1 P28845 2/20 0.35
HSD17B3 P37058 1/20 0.35
ALDH1A1 P00352 2/20 0.34
TSHR P16473 2/20 0.34
HTT P42858 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
NR3C2 P08235 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14569426 0.86 TDP1 (0.42) CYP2C19TDP1ESR2ESR1MCL1
SCHEMBL1027177 0.83 CYP2C19 (0.46) CYP2C19TDP1ESR2ESR1KMT2A
SCHEMBL4408425 0.80 TDP1 (0.46) TDP1MCL1ALDH1A1TSHRHTT
SCHEMBL14131699 0.77 CYP2C19 (0.43) CYP2C19TDP1ESR2ESR1KMT2A
SCHEMBL14595314 0.75 TDP1 (0.35) TDP1MCL1HSD11B1HSD17B3
SCHEMBL14569427 0.74 MMP9 (0.42) TDP1HSD11B1ALDH1A1
SCHEMBL14131944 0.74 TDP1 (0.39) CYP2C19TDP1KMT2AMCL1ALDH1A1
SCHEMBL14382995 0.74 TDP1 (0.46) TDP1ALDH1A1TSHRHTTSMN1; SMN2
SCHEMBL13876395 0.74 CYP2C19 (0.49) CYP2C19ESR2ESR1KMT2AHSD11B1
SCHEMBL16264853 0.74 CYP2C19 (0.49) CYP2C19ESR2ESR1KMT2AHSD11B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7402374-B2 Method for colored image formation FUJIFILM CORPORATION (JP) 2008-07-22 US disclosed