SCHEMBL1413208

SCHEMBL1413208

COC(=O)C=CC(C)=O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7728489 1.00 NFE2L2 (0.77)
SCHEMBL1413207 1.00
SCHEMBL7728484 1.00 NFE2L2 (0.77)
SCHEMBL12659068 1.00
SCHEMBL16257480 0.92 NFE2L2 (0.65)
Dimethyl Fumarate SCHEMBL29062056 0.88 NFE2L2 (0.87)
Dimethyl Fumarate SCHEMBL41836 0.87 NFE2L2 (1.00)
Dimethyl Fumarate SCHEMBL11668350 0.87 NFE2L2 (1.00)
Dimethyl Maleate SCHEMBL75864 0.87 NFE2L2 (1.00)
Dimethyl Fumarate SCHEMBL41835 0.87 NFE2L2 (1.00)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250376626-A1 STEAM TREATMENT OF WASTE SRU INNOVATIONS LTD (GB) 2025-12-11 US disclosed
US-20250074881-A1 THERAPEUTIC COMPOUNDS AND METHODS OF USE GENENTECH, INC. (US) 2025-03-06 US disclosed
US-12110276-B2 Pyrazolo compounds and methods of use thereof GENENTECH, INC. (US) 2024-10-08 US disclosed
EP-4436957-A1 THERAPEUTIC INDAZOLE COMPOUNDS AND METHODS OF USE IN THE TREATMENT OF CANCER Genentech, Inc. (US) 2024-10-02 EP disclosed
US-20230202984-A1 THERAPEUTIC COMPOUNDS AND METHODS OF USE GENENTECH, INC. (US) 2023-06-29 US disclosed
WO-2023097195-A1 THERAPEUTIC INDAZOLE COMPOUNDS AND METHODS OF USE IN THE TREATMENT OF CANCER GENENTECH, INC. (US) 2023-06-01 WO disclosed
EP-3208303-B1 RUBBER COMPOSITION FOR TIRE ZEON CORP (JP) 2020-02-19 EP disclosed
US-10125245-B2 Rubber composition for tire ZEON CORPORATION (JP) 2018-11-13 US disclosed
US-20170247479-A1 RUBBER COMPOSITON FOR TIRES ZEON CORPORATION (JP) 2017-08-31 US disclosed
EP-3208304-A1 RUBBER COMPOSITION FOR TIRE Zeon Corporation (JP) 2017-08-23 EP disclosed
US-5693729-A STEREOSPECIFIC CATALYZING IN PRESENCE OF A MIXTURE CONSISTING OF A TITANIUM AND A MAGNESIUM COMPOUND, AN ORGANOALUMINUM COMPOUND OR AN ALUMOXANE, AN ORGANOSILICON COMPOUND SHOWA DENKO K.K. (JP) 1997-12-02 US disclosed
EP-0578473-B1 Catalyst for polymerization of olefin and process for producing olefin polymer SHOWA DENKO KK (JP) 1997-11-19 EP disclosed
EP-0640624-B1 Catalyst for polymerization of olefin and process for the preparation of olefin polymer SHOWA DENKO KK (JP) 1997-06-18 EP disclosed
EP-0717053-A2 Catalyst for olefin polymerization and process for producing polyolefin using the same JAPAN POLYOLEFINS CO., LTD. (JP) 1996-06-19 EP disclosed
EP-0704424-A1 3-alkoxypropionic ester derivative, olefin polymerization catalyst, and process for preparation of polyolefin SHOWA DENKO KABUSHIKI KAISHA (JP) 1996-04-03 EP disclosed
US-5476825-A Consists of magnesium, titanium and halogen compounds, an organoaluminum compound, a reaction product of organoaluminum or organoboron compound with organosilicon compound SHOWA DENKO K.K. (JP) 1995-12-19 US disclosed
US-5407883-A Containing magnesium, titanium, aluminum and silicon compounds including polymeric aluminum and alumoxanes SHOWA DENKO K.K. (JP) 1995-04-18 US disclosed
EP-0640624-A1 Catalyst for polymerization of olefin and process for the preparation of olefin polymer SHOWA DENKO KABUSHIKI KAISHA (JP) 1995-03-01 EP disclosed
EP-0578473-A1 Catalyst for polymerization of olefin and process for producing olefin polymer SHOWA DENKO KABUSHIKI KAISHA (JP) 1994-01-12 EP disclosed
CN-1036573-A The novel preparation method of imidazopyridine derivatives YAMANOUCHI PHARMA CO LTD (JP) 1989-10-25 CN disclosed