Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.66 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | DRD4 | P21917 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30831905 | 1.00 | PARP1 (0.66) | PARP1RXFP1LMNAGAAL3MBTL1 | |
| SCHEMBL1413261 | 1.00 | PARP1 (0.66) | PARP1RXFP1LMNAGAAL3MBTL1 | |
| SCHEMBL18225573 | 0.79 | PARP1 (0.70) | PARP1RXFP1LMNAPRMT5 | |
| SCHEMBL630485 | 0.79 | PARP1 (1.00) | PARP1 | |
| SCHEMBL7468933 | 0.79 | PARP1 (0.56) | PARP1RXFP1 | |
| Hydrochloric Acid SCHEMBL7358627 | 0.78 | PARP1 (0.97) | PARP1 | |
| SCHEMBL18249353 | 0.75 | PARP1 (0.51) | PARP1PRMT5 | |
| Hydrochloric Acid SCHEMBL28102418 | 0.74 | PARP1 (0.62) | PARP1RXFP1LMNAPRMT5 | |
| SCHEMBL453514 | 0.74 | PARP1 (0.72) | PARP1RXFP1 | |
| SCHEMBL12618985 | 0.73 | PARP1 (0.38) | PARP1LMNAGAAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240122179-A1 | AUXINIC HERBICIDES AND METHODS OF USE THEREOF | CORTEVA AGRISCIENCE LLC (US) | 2024-04-18 | — | — | US | disclosed |
| CN-117813004-A | Auxin herbicide and application method thereof | 科迪华农业科技有限责任公司 | 2024-04-02 | — | — | CN | disclosed |
| WO-2022170075-A1 | AUXINIC HERBICIDES AND METHODS OF USE THEREOF | CORTEVA AGRISCIENCE LLC (US) | 2022-08-11 | — | — | WO | disclosed |
| EP-3782991-A1 | NOVEL MODULATORS OF SPHINGOSINE PHOSPHATE RECEPTORS | The Scripps Research Institute (US) | 2021-02-24 | — | — | EP | disclosed |
| US-10544136-B2 | Modulators of sphingosine phosphate receptors | THE SCRIPPS RESEARCH INSTITUTE (US) | 2020-01-28 | — | — | US | disclosed |
| US-20190084947-A1 | NOVEL MODULATORS OF SPHINGOSINE PHOSPHATE RECEPTORS | THE SCRIPPS RESEARCH INSTITUTE | 2019-03-21 | — | — | US | disclosed |
| US-9975863-B2 | Modulators of sphingosine phosphate receptors | THE SCRIPPS RESEARCH INSTITUTE (US) | 2018-05-22 | — | — | US | disclosed |
| US-20180009770-A1 | NOVEL MODULATORS OF SPHINGOSINE PHOSPHATE RECEPTORS | THE SCRIPPS RESEARCH INSTITUTE | 2018-01-11 | — | — | US | disclosed |
| US-20170050941-A1 | NOVEL MODULATORS OF SPHINGOSINE PHOSPHATE RECEPTORS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2017-02-23 | — | — | US | disclosed |
| US-9382217-B2 | Modulators of sphingosine phosphate receptors | THE SCRIPPS RESEARCH INSTITUTE (US) | 2016-07-05 | — | — | US | disclosed |
| US-8530503-B2 | Modulators of sphingosine phosphate receptors | THE SCRIPPS RESEARCH INSTITUTE (US) | 2013-09-10 | — | — | US | disclosed |
| US-8481573-B2 | Modulators of sphingosine phosphate receptors | THE SCRIPPS RESEARCH INSTITUTE (US) | 2013-07-09 | — | — | US | disclosed |
| US-8466183-B2 | Modulators of sphingosine phosphate receptors | THE SCRIPPS RESEARCH INSTITUTE (US) | 2013-06-18 | — | — | US | disclosed |
| US-20120329840-A1 | NOVEL MODULATORS OF SPHINGOSINE PHOSPHATE RECEPTORS | THE SCRIPPS RESEARCH INSTITUTE (US) | 2012-12-27 | — | — | US | disclosed |
| US-20120329838-A1 | NOVEL MODULATORS OF SPHINGOSINE PHOSPHATE RECEPTORS | THE SCRIPPS RESEARCH INSTITUTE (US) | 2012-12-27 | — | — | US | disclosed |
| US-20120329839-A1 | NOVEL MODULATORS OF SPHINGOSINE PHOSPHATE RECEPTORS | THE SCRIPPS RESEARCH INSTITUTE (US) | 2012-12-27 | — | — | US | disclosed |
| EP-2291080-A1 | NOVEL MODULATORS OF SPHINGOSINE PHOSPHATE RECEPTORS | The Scripps Research Institute (US) | 2011-03-09 | — | — | EP | disclosed |
| WO-2009151529-A9 | NOVEL MODULATORS OF SPHINGOSINE PHOSPHATE RECEPTORS | THE SCRIPPS RESEARCH INSTITUTE (US) | 2010-04-08 | — | — | WO | disclosed |
| US-20100010001-A1 | NOVEL MODULATORS OF SPHINGOSINE PHOSPHATE RECEPTORS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2010-01-14 | — | — | US | disclosed |
| WO-2009151529-A1 | NOVEL MODULATORS OF SPHINGOSINE PHOSPHATE RECEPTORS | THE SCRIPPS RESEARCH INSTITUTE (US) | 2009-12-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10544136-B2 | Modulators of sphingosine phosphate receptors | S1PR1, S1PR3, S1PR2 | PARP1 2193/4885RXFP1 164/4885LMNA 3367/4885 |
| US-20190084947-A1 | NOVEL MODULATORS OF SPHINGOSINE PHOSPHATE RECEPTORS | S1PR1, S1PR3, S1PR2 | PARP1 2419/4885RXFP1 167/4885LMNA 3700/4885 |
| US-20240122179-A1 | AUXINIC HERBICIDES AND METHODS OF USE THEREOF | DDT, HACL2, ALAD | PARP1 4728/4885RXFP1 2097/4885LMNA 4370/4885 |
| US-20180009770-A1 | NOVEL MODULATORS OF SPHINGOSINE PHOSPHATE RECEPTORS | S1PR1, S1PR3, S1PR2 | PARP1 2200/4885RXFP1 152/4885LMNA 3678/4885 |
| US-20120329838-A1 | NOVEL MODULATORS OF SPHINGOSINE PHOSPHATE RECEPTORS | S1PR1, S1PR3, S1PR2 | PARP1 2419/4885RXFP1 167/4885LMNA 3700/4885 |
| US-20120329839-A1 | NOVEL MODULATORS OF SPHINGOSINE PHOSPHATE RECEPTORS | S1PR1, S1PR3, S1PR2 | PARP1 2419/4885RXFP1 167/4885LMNA 3700/4885 |
| US-20120329840-A1 | NOVEL MODULATORS OF SPHINGOSINE PHOSPHATE RECEPTORS | S1PR1, S1PR3, S1PR2 | PARP1 2419/4885RXFP1 167/4885LMNA 3700/4885 |
| US-20170050941-A1 | NOVEL MODULATORS OF SPHINGOSINE PHOSPHATE RECEPTORS | S1PR1, S1PR3, S1PR2 | PARP1 2419/4885RXFP1 167/4885LMNA 3700/4885 |
| US-20100010001-A1 | NOVEL MODULATORS OF SPHINGOSINE PHOSPHATE RECEPTORS | S1PR1, S1PR3, S1PR4 | PARP1 2450/4885RXFP1 178/4885LMNA 3786/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.