Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 2/20 | 0.72 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | DHODH | Q02127 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL22165594 | 0.98 | PARP1 (0.70) | PARP1KDM4EHPGDDHODHRXFP1 | |
| Hydrochloric Acid SCHEMBL2129546 | 0.98 | PARP1 (0.70) | PARP1KDM4EHPGDDHODHRXFP1 | |
| SCHEMBL28284556 | 0.98 | PARP1 (0.70) | PARP1KDM4EHPGDDHODHRXFP1 | |
| SCHEMBL9218238 | 0.98 | PARP1 (0.70) | PARP1KDM4EHPGDDHODHRXFP1 | |
| Acetic Acid SCHEMBL7575146 | 0.95 | PARP1 (0.66) | PARP1KDM4EHPGDDHODHRXFP1 | |
| Trifluoroacetic Acid SCHEMBL20482044 | 0.91 | PARP1 (0.60) | PARP1KDM4EHPGDDHODHRXFP1 | |
| SCHEMBL28267894 | 0.88 | PARP1 (0.61) | PARP1KDM4EHPGDRXFP1CNR2 | |
| Tromethamine SCHEMBL16115019 | 0.87 | PARP1 (0.60) | PARP1KDM4EHPGDRXFP1 | |
| SCHEMBL30100550 | 0.86 | PARP1 (0.54) | PARP1KDM4EHPGDDHODHALDH1A1 | |
| SCHEMBL9725323 | 0.85 | PARP1 (0.58) | PARP1KDM4EDHODHALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 572 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4118069-B1 | PARA-HYDROQUINONE DERIVATIVES AS VEGF, TNF AND/OR IL INHIBITORS FOR THE TREATMENT OF NEUROINFLAMMATORY DISEASES | OM PHARMA SA (CH) | 2024-10-23 | — | — | EP | claimed |
| CN-117696012-A | Metal organic framework material and preparation method and application thereof | 浙江大学 | 2024-03-15 | — | — | CN | claimed |
| CN-112300235-B | Benzimidazole derivative BI321 and preparation method and application thereof | 中国人民解放军东部战区总医院 | 2021-12-21 | — | — | CN | claimed |
| CN-112920241-B | Benzimidazole derivative BI308 and preparation method and application thereof | 中国人民解放军东部战区总医院 | 2021-12-21 | — | — | CN | claimed |
| CN-112812145-B | Benzimidazole derivative BI293 and preparation method and application thereof | 中国人民解放军东部战区总医院 | 2021-12-21 | — | — | CN | claimed |
| CN-112375112-B | Benzimidazole derivative BI361 and preparation method and application thereof | 中国人民解放军东部战区总医院 | 2021-12-21 | — | — | CN | claimed |
| CN-112920241-A | Benzimidazole derivative BI308 and preparation method and application thereof | 中国人民解放军东部战区总医院 | 2021-06-08 | — | — | CN | claimed |
| CN-112812145-A | Benzimidazole derivative BI293 and preparation method and application thereof | 中国人民解放军东部战区总医院 | 2021-05-18 | — | — | CN | claimed |
| CN-112592485-A | Preparation of polyion liquid functionalized MOFs material and application of polyion liquid functionalized MOFs material in synthesis of isopulegol | 福州大学 | 2021-04-02 | — | — | CN | claimed |
| CN-112375112-A | Benzimidazole derivative BI361 and preparation method and application thereof | 中国人民解放军东部战区总医院 | 2021-02-19 | — | — | CN | claimed |
| CN-1215338-A | Pharmaceutical combination containing a compound having angiotensin II and antagonisti activity | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1999-04-28 | — | — | CN | claimed |
| EP-0546358-B1 | Pharmaceutical compositions with angiotensin-II-antagonistic activity | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1997-08-27 | — | — | EP | claimed |
| EP-0759754-A1 | A METHOD OF MODIFYING ANGIOTENSIN RECEPTOR ACTIVITY FOR TREATMENT OF PREMENSTRUAL SYNDROME AND MEDIATION OF PAIN | DePadova, Anthony S. (US) | 1997-03-05 | — | — | EP | claimed |
| US-5534534-A | HYPOTENSIVE AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-07-09 | — | — | US | claimed |
| WO-1995029674-A1 | A METHOD OF MODIFYING ANGIOTENSIN RECEPTOR ACTIVITY FOR TREATMENT OF PREMENSTRUAL SYNDROME AND MEDIATION OF PAIN | DEPADOVA ANTHONY S (US) | 1995-11-09 | — | — | WO | claimed |
| EP-0612524-A1 | Angiotensin II antagonists for the treatment of viral diseases | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1994-08-31 | — | — | EP | claimed |
| CN-1086998-A | Combination of oral medication and preparation method | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1994-05-25 | — | — | CN | claimed |
| EP-0546358-A2 | Pharmaceutical compositions with angiotensin-II-antagonistic activity | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1993-06-16 | — | — | EP | claimed |
| CN-1072338-A | Combination of oral medication and preparation method | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1993-05-26 | — | — | CN | claimed |
| US-4662905-A | REACTION PRODUCT OF COPPER SALT AND AN IMIDAZOLE, PYRAZOLE, TRIAZOLE, OR TETRAZOLE | Itaru Todoriki, Director of Agency of Industrial Science and Technology (JP) | 1987-05-05 | — | — | US | claimed |