Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 2/20 | 0.52 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.52 |
| ▸ | AHCY | P23526 | 7/20 | 0.47 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.46 |
| ▸ | DNMT3B | Q9UBC3 | 1/20 | 0.46 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.41 |
| ▸ | DPP4 | P27487 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.41 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.41 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.41 |
| ▸ | GAPDH | P04406 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | STAT6 | P42226 | 1/20 | 0.41 |
| ▸ | PI4KA | P42356 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.41 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14134511 | 0.88 | ADORA2A (0.47) | ADORA2AADORA2BAHCYDNMT1DNMT3B | |
| SCHEMBL13396668 | 0.85 | AHCY (0.62) | ADORA2AADORA2BAHCYADORA1ADORA3 | |
| SCHEMBL14134565 | 0.78 | ADORA2A (0.45) | ADORA2AADORA2BAHCYDNMT1DNMT3B | |
| SCHEMBL14134547 | 0.76 | AHCY (0.53) | ADORA2AADORA2BAHCYDNMT1DNMT3B | |
| SCHEMBL17659034 | 0.75 | ADORA2A (0.68) | ADORA2AADORA2BDNMT1DNMT3BADORA1 | |
| SCHEMBL13820095 | 0.75 | ADORA2A (0.68) | ADORA2AADORA2BDNMT1DNMT3BADORA1 | |
| SCHEMBL18490353 | 0.75 | ADORA2A (0.68) | ADORA2AADORA2BDNMT1DNMT3BADORA1 | |
| SCHEMBL12556357 | 0.75 | ADORA2A (0.68) | ADORA2AADORA2BDNMT1DNMT3BADORA1 | |
| SCHEMBL26507720 | 0.75 | ADORA2A (0.68) | ADORA2AADORA2BDNMT1DNMT3BADORA1 | |
| SCHEMBL4320935 | 0.75 | ADORA2A (0.68) | ADORA2AADORA2BDNMT1DNMT3BADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8324179-B2 | Nucleoside analogs for antiviral treatment | GILEAD SCIENCES, INC. (US) | 2012-12-04 | — | — | US | disclosed |