Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHCY | P23526 | 13/20 | 0.53 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.52 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.52 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.47 |
| ▸ | DNMT3B | Q9UBC3 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | DNPH1 | O43598 | 1/20 | 0.43 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.43 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.43 |
| ▸ | LDHA | P00338 | 1/20 | 0.43 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.43 |
| ▸ | FBP1 | P09467 | 1/20 | 0.43 |
| ▸ | SRC | P12931 | 1/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.43 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.43 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.43 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.43 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14134444 | 0.88 | P2RY2 (0.49) | AHCYADORA2AADORA2BDNPH1PRKAB2 | |
| SCHEMBL13396418 | 0.85 | AHCY (0.73) | AHCYADORA2AADORA2BHIF1ATMEM97 | |
| SCHEMBL3316367 | 0.85 | AHCY (0.73) | AHCYADORA2AADORA2BHIF1ATMEM97 | |
| SCHEMBL3316378 | 0.85 | AHCY (0.73) | AHCYADORA2AADORA2BHIF1ATMEM97 | |
| SCHEMBL14134335 | 0.76 | ADORA2A (0.52) | AHCYADORA2AADORA2BDNMT1DNMT3B | |
| SCHEMBL13396506 | 0.75 | P2RY12 (0.52) | AHCYADORA2AADORA2BDNPH1P2RY2 | |
| SCHEMBL3317321 | 0.75 | P2RY12 (0.52) | AHCYADORA2AADORA2BDNPH1P2RY2 | |
| SCHEMBL3317307 | 0.75 | P2RY12 (0.52) | AHCYADORA2AADORA2BDNPH1P2RY2 | |
| SCHEMBL14928636 | 0.74 | DNPH1 (0.73) | DNPH1PRKAB2TRPM2LDHAADRB2 | |
| SCHEMBL15249230 | 0.74 | DNPH1 (0.73) | DNPH1PRKAB2TRPM2LDHAADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8324179-B2 | Nucleoside analogs for antiviral treatment | GILEAD SCIENCES, INC. (US) | 2012-12-04 | — | — | US | disclosed |