Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 7/20 | 0.59 |
| ▸ | LMNA | P02545 | 6/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.59 |
| ▸ | NR3C1 | P04150 | 4/20 | 0.59 |
| ▸ | PGR | P06401 | 4/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | CNR1 | P21554 | 1/20 | 0.59 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.59 |
| ▸ | USP2 | O75604 | 1/20 | 0.59 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.58 |
| ▸ | TNF | P01375 | 2/20 | 0.51 |
| ▸ | IKBKB | O14920 | 1/20 | 0.50 |
| ▸ | JAK2 | O60674 | 1/20 | 0.50 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.50 |
| ▸ | PRKCA | P17252 | 1/20 | 0.50 |
| ▸ | PRKACA | P17612 | 1/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | JAK1 | P23458 | 1/20 | 0.50 |
| ▸ | PRKCH | P24723 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13407212 | 1.00 | HIF1A (0.59) | HIF1ALMNACYP3A4NR3C1PGR | |
| SCHEMBL14135287 | 0.93 | HIF1A (0.59) | HIF1ALMNACYP3A4NR3C1PGR | |
| SCHEMBL13407289 | 0.93 | HIF1A (0.59) | HIF1ALMNACYP3A4NR3C1PGR | |
| SCHEMBL13388936 | 0.92 | LMNA (0.57) | HIF1ALMNACYP3A4NR3C1PGR | |
| SCHEMBL13407112 | 0.91 | HIF1A (0.57) | HIF1ALMNACYP3A4NR3C1PGR | |
| SCHEMBL13407294 | 0.90 | HIF1A (0.56) | HIF1ALMNACYP3A4NR3C1PGR | |
| SCHEMBL13407211 | 0.90 | NR3C1 (0.64) | HIF1ALMNACYP3A4NR3C1PGR | |
| SCHEMBL13389070 | 0.90 | LMNA (0.55) | HIF1ALMNACYP3A4NR3C1PGR | |
| SCHEMBL13407299 | 0.90 | HIF1A (0.60) | HIF1ALMNACYP3A4NR3C1PGR | |
| SCHEMBL13659905 | 0.90 | HIF1A (0.70) | HIF1ALMNACYP3A4NR3C1PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008095806-A1 | NITRIC OXIDE RELEASING STEROIDS | NICOX S.A. (FR) | 2008-08-14 | — | — | WO | disclosed |