Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | FKBP1A | P62942 | 6/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | KLK7 | P49862 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16748121 | 0.86 | HSD17B10 (0.51) | HSD17B10SMN1; SMN2NPC1FKBP1AMEN1 | |
| SCHEMBL8490085 | 0.86 | HSD17B10 (0.51) | HSD17B10SMN1; SMN2NPC1FKBP1AMEN1 | |
| SCHEMBL25736771 | 0.86 | HSD17B10 (0.54) | HSD17B10SMN1; SMN2NPC1FKBP1AMEN1 | |
| SCHEMBL12215284 | 0.85 | FKBP1A (0.52) | HSD17B10SMN1; SMN2NPC1FKBP1AMEN1 | |
| SCHEMBL18676059 | 0.85 | FKBP1A (0.52) | HSD17B10SMN1; SMN2NPC1FKBP1AMEN1 | |
| SCHEMBL25960272 | 0.85 | FKBP1A (0.50) | HSD17B10SMN1; SMN2NPC1FKBP1AMEN1 | |
| SCHEMBL8223617 | 0.85 | FKBP1A (0.58) | HSD17B10SMN1; SMN2NPC1FKBP1AMEN1 | |
| SCHEMBL440340 | 0.85 | FKBP1A (0.58) | HSD17B10SMN1; SMN2NPC1FKBP1AMEN1 | |
| SCHEMBL3206028 | 0.85 | HSD17B10 (0.54) | HSD17B10SMN1; SMN2NPC1FKBP1AMEN1 | |
| SCHEMBL4962228 | 0.85 | HSD17B10 (0.54) | HSD17B10SMN1; SMN2NPC1FKBP1AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008095841-A2 | NITRIC OXIDE DONOR COMPOUNDS | NICOX S.A. (FR) | 2008-08-14 | — | — | WO | disclosed |