Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KLK7 | P49862 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | FKBP1A | P62942 | 2/20 | 0.45 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4962228 | 1.00 | HSD17B10 (0.54) | HSD17B10SMN1; SMN2ALDH1A1NPC1KMT2A | |
| SCHEMBL23484492 | 0.96 | FKBP1A (0.50) | HSD17B10SMN1; SMN2ALDH1A1NPC1KMT2A | |
| SCHEMBL1401256 | 0.88 | FKBP1A (0.58) | HSD17B10SMN1; SMN2ALDH1A1NPC1KMT2A | |
| SCHEMBL440340 | 0.88 | FKBP1A (0.58) | HSD17B10SMN1; SMN2ALDH1A1NPC1KMT2A | |
| SCHEMBL8223617 | 0.88 | FKBP1A (0.58) | HSD17B10SMN1; SMN2ALDH1A1NPC1KMT2A | |
| SCHEMBL9933626 | 0.87 | HSD17B10 (0.53) | HSD17B10SMN1; SMN2ALDH1A1NPC1KMT2A | |
| SCHEMBL25960270 | 0.87 | HSD17B10 (0.53) | HSD17B10SMN1; SMN2ALDH1A1NPC1KMT2A | |
| SCHEMBL9933627 | 0.87 | HSD17B10 (0.53) | HSD17B10SMN1; SMN2ALDH1A1NPC1KMT2A | |
| SCHEMBL7286305 | 0.86 | HSD17B10 (0.61) | HSD17B10SMN1; SMN2ALDH1A1NPC1KMT2A | |
| SCHEMBL19414808 | 0.86 | HSD17B10 (0.61) | HSD17B10SMN1; SMN2ALDH1A1NPC1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122070276-A | Prodrugs of xanomeline, prodrugs of trospium chloride and methods of using the same | 人类生物科学股份有限公司 | 2026-05-19 | — | — | CN | disclosed |
| EP-4705289-A1 | PRODRUGS OF XANOMELINE, PRODRUGS OF TROSPIUM AND METHODS OF USE THEREOF | Terran Biosciences Inc. (US) | 2026-03-11 | — | — | EP | disclosed |
| WO-2024226691-A1 | PRODRUGS OF XANOMELINE, PRODRUGS OF TROSPIUM AND METHODS OF USE THEREOF | TERRAN BIOSCIENCES INC. (US) | 2024-10-31 | — | — | WO | disclosed |
| US-20240067651-A1 | PRODRUGS OF MYELOPEROXIDASE INHIBITORS | BIOHAVEN THERAPEUTICS LTD. | 2024-02-29 | — | — | US | disclosed |
| EP-4041735-A1 | PRODRUGS OF MYELOPEROXIDASE INHIBITORS | Biohaven Therapeutics Ltd. (US) | 2022-08-17 | — | — | EP | disclosed |
| US-7674912-B2 | Pro-drugs of N-thiazol-2-yl-benzamide derivatives | H. LUNDBECK A/S (DK) | 2010-03-09 | — | — | US | disclosed |
| US-20060264485-A1 | Pro-drugs of N-thiazol-2-yl-benzamide derivatives | H. LUNDBECK A/S (DK) | 2006-11-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060264485-A1 | Pro-drugs of N-thiazol-2-yl-benzamide derivatives | ADORA2A, ADORA2B, ADORA1 | HSD17B10 4188/4885SMN1; SMN2 1680/4885ALDH1A1 727/4885 |
| US-20240067651-A1 | PRODRUGS OF MYELOPEROXIDASE INHIBITORS | MPO, CAT, SOD1 | HSD17B10 992/4885SMN1; SMN2 80/4885ALDH1A1 570/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.