Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 12/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | MAOA | P21397 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MMP13 | P45452 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.46 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.46 |
| ▸ | GRM5 | P41594 | 1/20 | 0.46 |
| ▸ | CASP3 | P42574 | 1/20 | 0.45 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18387682 | 0.77 | HRH3 (0.50) | MAPTTDP1ALDH1A1MAOAL3MBTL1 | |
| SCHEMBL7873208 | 0.76 | MEN1 (0.52) | KMT2AMAPTMEN1ALDH1A1L3MBTL1 | |
| SCHEMBL15323331 | 0.75 | MEN1 (0.54) | KMT2AMEN1MAOAMAOBNPC1 | |
| SCHEMBL11849653 | 0.74 | ESR1 (0.72) | KMT2AMAPTMEN1TDP1ALDH1A1 | |
| SCHEMBL9720000 | 0.74 | KMT2A (0.58) | KMT2AMAPTMEN1TDP1ALDH1A1 | |
| SCHEMBL2819895 | 0.73 | ACHE (0.51) | KMT2AMAPTMEN1TDP1ALDH1A1 | |
| SCHEMBL13078257 | 0.73 | GAA (0.57) | KMT2AMAPTMEN1TDP1ALDH1A1 | |
| SCHEMBL2625807 | 0.73 | NOTUM (0.59) | KMT2AMEN1SRD5A1 | |
| SCHEMBL21792031 | 0.73 | KDM4E (0.56) | KMT2AMAPTMEN1ALDH1A1NPC1 | |
| SCHEMBL28499625 | 0.72 | HRH3 (0.70) | MAOAMAOBNPC1RAB9ASRD5A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1950199-A1 | Proline derivatives and use thereof as drugs | Mitsubishi Tanabe Pharma Corporation (JP) | 2008-07-30 | — | — | EP | disclosed |