SCHEMBL14137283

SCHEMBL14137283

Cc1cc(C(C)c2ccc(OC(=O)c3ccccc3)c(C)c2)ccc1O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 7/20 0.43
MEN1 O00255 5/20 0.43
MAPT P10636 4/20 0.43
SMN1; SMN2 Q16637 3/20 0.43
ESR1 P03372 3/20 0.43
ESR2 Q92731 3/20 0.43
GAA P10253 2/20 0.43
JAK2 O60674 1/20 0.43
USP2 O75604 1/20 0.43
ALOX15 P16050 1/20 0.43
NPSR1 Q6W5P4 1/20 0.43
HSD17B10 Q99714 1/20 0.43
SLC6A3 Q01959 1/20 0.40
TDP1 Q9NUW8 2/20 0.40
ALDH1A1 P00352 2/20 0.40
SERPINE1 P05121 1/20 0.40
KDM4E B2RXH2 1/20 0.40
RAB9A P51151 1/20 0.40
CYP3A4 P08684 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14125308 0.88 KMT2A (0.48) KMT2AMEN1MAPTSLC6A3TDP1
SCHEMBL12710147 0.85 ALDH1A1 (0.54) KMT2AMEN1MAPTSMN1; SMN2TDP1
SCHEMBL21387331 0.85 MAPT (0.41) KMT2AMEN1MAPTSMN1; SMN2ESR1
SCHEMBL12710467 0.85 ALDH1A1 (0.46) KMT2AMEN1MAPTESR1ESR2
SCHEMBL18780388 0.84 ESR1 (0.41) KMT2AMEN1MAPTSMN1; SMN2ESR1
SCHEMBL14615844 0.83 HSD17B1 (0.50) KMT2AMEN1MAPTSMN1; SMN2ESR1
SCHEMBL12520031 0.82 ALDH1A1 (0.51) KMT2AMEN1MAPTSMN1; SMN2HSD17B10
SCHEMBL12521525 0.82 PIM1 (0.42) MAPTSMN1; SMN2ESR1GAANPSR1
SCHEMBL14040042 0.82 CYP1A2 (0.41) KMT2AMEN1MAPTSMN1; SMN2ESR1
SCHEMBL9887004 0.81 ALDH1A1 (0.49) KMT2AMEN1MAPTSMN1; SMN2GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8753789-B2 Electrophotographic photosensitive member, process cartridge, electrophotographic apparatus, and method of manufacturing electrophotographic photosensitive member CANON KABUSHIKI KAISHA (JP) 2014-06-17 US disclosed
US-8669027-B2 Electrophotographic photosensitive member, process cartridge, electrophotographic apparatus, and method of manufacturing electrophotographic photosensitive member CANON KABUSHIKI KAISHA (JP) 2014-03-11 US disclosed
US-20120301182-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, ELECTROPHOTOGRAPHIC APPARATUS, AND METHOD OF MANUFACTURING ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER CANON KABUSHIKI KAISHA (JP) 2012-11-29 US disclosed
US-20120301181-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, ELECTROPHOTOGRAPHIC APPARATUS, AND METHOD OF MANUFACTURING ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER CANON KABUSHIKI KAISHA (JP) 2012-11-29 US disclosed