Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 6/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.44 |
| ▸ | TTR | P02766 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.41 |
| ▸ | PARP3 | Q9Y6F1 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.38 |
| ▸ | HTR2C | P28335 | 2/20 | 0.38 |
| ▸ | DRD1 | P21728 | 2/20 | 0.38 |
| ▸ | TYR | P14679 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4554850 | 0.87 | ALDH1A3 (0.49) | ALDH1A3HTR2ASLC6A4TTRALDH1A1 | |
| SCHEMBL2356142 | 0.81 | SLC6A4 (0.49) | HTR2ASLC6A4ALDH1A1LMNAKMT2A | |
| SCHEMBL14047222 | 0.80 | HTR2A (0.66) | HTR2ASLC6A4ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL15515907 | 0.80 | SLC6A4 (0.47) | HTR2ASLC6A4ALDH1A1LMNAKMT2A | |
| SCHEMBL8311249 | 0.79 | TTR (0.58) | ALDH1A3TTRALDH1A1LMNACYP1A2 | |
| SCHEMBL14047199 | 0.79 | TTR (0.59) | TTRALDH1A1LMNACYP1A2CYP2C9 | |
| SCHEMBL4440523 | 0.77 | P2RX3 (0.42) | HTR2ASLC6A4ALDH1A1LMNACYP1A2 | |
| SCHEMBL13597306 | 0.76 | CA1 (0.49) | HTR2ASLC6A4ALDH1A1LMNAKDM4E | |
| SCHEMBL1556957 | 0.76 | CA1 (0.49) | HTR2ASLC6A4ALDH1A1LMNAKDM4E | |
| SCHEMBL25960695 | 0.76 | TTR (0.64) | ALDH1A3TTRALDH1A1LMNACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120301552-A1 | CaSR Antagonist | JAPAN TOBACCO INC. (JP) | 2012-11-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120301552-A1 | CaSR Antagonist | CASR, CALCR, CALCRL | ALDH1A3 3729/4885HTR2A 1085/4885SLC6A4 1682/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.