SCHEMBL1413874

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1413758	0.87	HTR6 (0.43)	HTR6NAMPT
	SCHEMBL1413690	0.86	GAA (0.54)	GAAHTR6NAMPTKMT2AALDH1A1
	SCHEMBL4009211	0.86	GAA (0.56)	GAAHTR6KMT2AALDH1A1MAPK1
	SCHEMBL1413567	0.85	GAA (0.54)	GAAHTR6KMT2AALDH1A1MAPK1
	SCHEMBL1413297	0.84	HTR6 (0.53)	HTR6
	SCHEMBL1413637	0.83	HTR6 (0.48)	HTR6KMT2AMEN1
	SCHEMBL1413725	0.81	HTR6 (0.50)	HTR6NAMPTKMT2AALDH1A1MEN1
	SCHEMBL1413495	0.80	ALDH1A1 (0.54)	GAAHTR6KMT2AALDH1A1MAPK1
	SCHEMBL1413655	0.79	HTR6 (0.56)	GAAHTR6POLBNAMPTKMT2A
	SCHEMBL13688572	0.78	GAA (0.48)	GAAHTR6NAMPTKMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.