Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 19/20 | 0.59 |
| ▸ | AR | P10275 | 8/20 | 0.59 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.59 |
| ▸ | NR3C1 | P04150 | 8/20 | 0.53 |
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14138796 | 0.88 | PGR (0.59) | PGRARNR3C2NR3C1 | |
| SCHEMBL14138792 | 0.88 | PGR (0.53) | PGRARNR3C2NR3C1 | |
| SCHEMBL13759957 | 0.87 | PGR (0.54) | PGRARNR3C2NR3C1 | |
| SCHEMBL14138817 | 0.87 | PGR (0.59) | PGRARNR3C2NR3C1 | |
| SCHEMBL14138956 | 0.86 | NR3C1 (0.58) | PGRARNR3C2NR3C1 | |
| SCHEMBL14138826 | 0.86 | PGR (0.49) | PGRARNR3C2NR3C1 | |
| SCHEMBL14139076 | 0.84 | PGR (0.61) | PGRARNR3C2NR3C1 | |
| SCHEMBL14138787 | 0.84 | PGR (0.60) | PGRARNR3C2NR3C1 | |
| SCHEMBL14138973 | 0.84 | PGR (0.60) | PGRARNR3C2NR3C1 | |
| SCHEMBL14138821 | 0.83 | PGR (0.47) | PGRARNR3C2NR3C1ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1944290-A1 | NOVEL 1-2-DIHYDROQUINOLINE DERIVATIVE HAVING GLUCOCORTICOID RECEPTOR BINDING ACTIVITY | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 2008-07-16 | — | — | EP | disclosed |