Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | USP2 | O75604 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | HCAR2 | Q8TDS4 | 7/20 | 0.49 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.49 |
| ▸ | DAO | P14920 | 1/20 | 0.46 |
| ▸ | BRAF | P15056 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | CYTH3 | O43739 | 1/20 | 0.42 |
| ▸ | BTK | Q06187 | 1/20 | 0.42 |
| ▸ | EPN1 | Q9Y6I3 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL70360 | 0.86 | CA12 (0.53) | MEN1KMT2AALDH1A1MAPTPOLB | |
| SCHEMBL29019950 | 0.84 | MEN1 (0.51) | MEN1KMT2AALDH1A1MAPTPOLB | |
| SCHEMBL69492 | 0.84 | MEN1 (0.58) | MEN1KMT2AALDH1A1MAPTPOLB | |
| SCHEMBL1413913 | 0.83 | NPC1 (0.55) | MEN1KMT2AMAPTPOLBHCAR2 | |
| SCHEMBL1413865 | 0.83 | ALPL (0.53) | MEN1KMT2AUSP2ALDH1A1MAPT | |
| SCHEMBL19996893 | 0.83 | MEN1 (0.50) | MEN1KMT2AMAPTPOLBHCAR2 | |
| SCHEMBL1413993 | 0.83 | HCAR2 (0.55) | MEN1KMT2AUSP2ALDH1A1MAPT | |
| SCHEMBL70800 | 0.83 | RAB9A (0.55) | MEN1KMT2AMAPTPOLBHCAR2 | |
| Hydrochloric Acid SCHEMBL1221862 | 0.82 | MEN1 (0.57) | MEN1KMT2AALDH1A1MAPTPOLB | |
| SCHEMBL12922085 | 0.82 | HCAR2 (0.56) | MEN1KMT2AUSP2ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2291372-A2 | INTESTINAL ALKALINE PHOSPHATASE MODULATORS AND USES THEREOF | Burnham Institute for Medical Research (US) | 2011-03-09 | — | — | EP | claimed |
| WO-2009143150-A2 | INTESTINAL ALKALINE PHOSPHATASE MODULATORS AND USES THEREOF | BURNHAM INSTITUTE FOR MEDICAL RESEARCH (US) | 2009-11-26 | — | — | WO | claimed |