Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SENP2 | Q9HC62 | 12/20 | 0.58 |
| ▸ | SENP1 | Q9P0U3 | 12/20 | 0.58 |
| ▸ | SENP5 | Q96HI0 | 11/20 | 0.58 |
| ▸ | MAOB | P27338 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4604976 | 0.88 | SENP5 (0.63) | SENP2SENP1SENP5MAOBALDH1A1 | |
| SCHEMBL4603558 | 0.87 | SENP2 (0.55) | SENP2SENP1SENP5MAOB | |
| SCHEMBL4634443 | 0.83 | SENP2 (0.62) | SENP2SENP1SENP5ALDH1A1USP2 | |
| SCHEMBL4633569 | 0.83 | KMT2A (0.56) | SENP2SENP1SENP5MAOBALDH1A1 | |
| SCHEMBL4604295 | 0.83 | SENP2 (0.53) | SENP2SENP1SENP5USP2 | |
| SCHEMBL4605734 | 0.80 | SENP2 (0.53) | SENP2SENP1SENP5ALDH1A1USP2 | |
| SCHEMBL4632950 | 0.80 | SENP5 (0.60) | SENP2SENP1SENP5ALDH1A1KMT2A | |
| SCHEMBL4604537 | 0.79 | SENP2 (0.60) | SENP2SENP1SENP5ALDH1A1USP2 | |
| SCHEMBL4605877 | 0.79 | SENP5 (0.48) | SENP2SENP1SENP5MAOBUSP2 | |
| SCHEMBL14159265 | 0.79 | SENP2 (0.59) | SENP2SENP1SENP5MAOBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1685122-B1 | BENZOFURANS AND BENZOTHIOPHENES | MERCK PATENT GMBH (DE) | 2008-07-09 | — | — | EP | disclosed |