Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2B | P29275 | 9/20 | 0.57 |
| ▸ | ADORA3 | P0DMS8 | 5/20 | 0.57 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.39 |
| ▸ | PDE4A | P27815 | 1/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.37 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL150604 | 0.77 | PDE1A (0.54) | ADORA2BADORA3ADORA2A | |
| SCHEMBL3949936 | 0.74 | ADORA2B (0.59) | ADORA2BADORA3ADORA2A | |
| SCHEMBL2547498 | 0.73 | ADORA2B (0.47) | ADORA2BADORA3ADORA2APDE4APDE4B | |
| SCHEMBL3423318 | 0.73 | ADORA2B (1.00) | ADORA2BADORA3ADORA2APDE4APDE4B | |
| SCHEMBL387340 | 0.72 | ADORA2B (0.55) | ADORA2BADORA2A | |
| SCHEMBL1954556 | 0.72 | ADORA2B (0.53) | ADORA2BADORA3ADORA2A | |
| SCHEMBL1954555 | 0.72 | ADORA2B (0.53) | ADORA2BADORA3ADORA2A | |
| SCHEMBL12257516 | 0.71 | ADORA2B (0.66) | ADORA2BADORA3ADORA2A | |
| SCHEMBL6381402 | 0.70 | ADORA2B (0.36) | ADORA2BADORA3ADORA2A | |
| SCHEMBL9904065 | 0.70 | ADORA2B (0.53) | ADORA2BADORA3ADORA2APDE4APDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1939197-A1 | 8-ethinylxanthine derivatives as selective A2A receptor antagonists | SCHWARZ PHARMA AG (DE) | 2008-07-02 | — | — | EP | disclosed |