Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | BLM | P54132 | 1/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 4/20 | 0.52 |
| ▸ | USP2 | O75604 | 3/20 | 0.52 |
| ▸ | MMP13 | P45452 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 4/20 | 0.51 |
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | CASP1 | P29466 | 1/20 | 0.51 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.51 |
| ▸ | CASP7 | P55210 | 1/20 | 0.51 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14625755 | 0.84 | NPSR1 (0.56) | NPSR1ALDH1A1LMNAMAPK1BLM | |
| SCHEMBL1588305 | 0.83 | RECQL (0.60) | NPSR1ALDH1A1LMNARECQLHTT | |
| SCHEMBL12313834 | 0.80 | HPGD (0.57) | NPSR1ALDH1A1LMNAMAPK1RECQL | |
| SCHEMBL1587643 | 0.80 | GAA (0.58) | NPSR1ALDH1A1LMNAMAPK1BLM | |
| SCHEMBL4919514 | 0.79 | ESRRG (0.58) | NPSR1RECQLHTTUSP2MMP13 | |
| SCHEMBL12265879 | 0.79 | LMNA (0.62) | NPSR1ALDH1A1LMNAMAPK1BLM | |
| SCHEMBL2229698 | 0.79 | HDAC1 (0.72) | NPSR1ALDH1A1LMNARECQLHTT | |
| SCHEMBL14625757 | 0.76 | HPGD (0.67) | ALDH1A1LMNAHTTKMT2AHPGD | |
| SCHEMBL4194312 | 0.76 | VNN1 (0.62) | NPSR1ALDH1A1LMNARECQLHTT | |
| SCHEMBL3459320 | 0.76 | NPSR1 (0.58) | NPSR1ALDH1A1LMNARECQLHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1947101-A1 | HYDRAZIDE COMPOUND AND THROMBOPOIETIN RECEPTOR ACTIVATOR | Nissan Chemical Industries, Ltd. (JP) | 2008-07-23 | — | — | EP | disclosed |