Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.34 |
| ▸ | PDE2A | O00408 | 1/20 | 0.33 |
| ▸ | LIPE | Q05469 | 6/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | OXTR | P30559 | 1/20 | 0.33 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
| ▸ | AR | P10275 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1414852 | 0.86 | DPP4 (0.34) | DPP4DPP7PDE2AAR | |
| SCHEMBL836935 | 0.84 | P4HTM (0.37) | — | |
| SCHEMBL836784 | 0.82 | PDE2A (0.39) | DPP4DPP7PDE2AJAK2AR | |
| SCHEMBL15789710 | 0.80 | DGAT1 (0.33) | — | |
| SCHEMBL15520845 | 0.79 | GRIN2B (0.32) | — | |
| SCHEMBL15789731 | 0.78 | ACACB (0.34) | LIPE | |
| SCHEMBL837193 | 0.78 | RECQL (0.39) | PDE2AKMT2AMEN1AR | |
| SCHEMBL480536 | 0.78 | BDKRB1 (0.37) | KMT2AMEN1OXTRAVPR1ASCN9A | |
| SCHEMBL732586 | 0.77 | MEN1 (0.41) | PDE2ALIPEKMT2AMEN1OXTR | |
| SCHEMBL15520676 | 0.76 | GPR55 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2205562-B1 | 1,1,1-TRIFLUORO-2-HYDROXY-3-PHENYLPROPANE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2011-03-16 | — | — | EP | claimed |