Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | SLC8B1 | Q6J4K2 | 1/20 | 0.39 |
| ▸ | AVPR1A | P37288 | 2/20 | 0.39 |
| ▸ | PTGDR2 | Q9Y5Y4 | 4/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.33 |
| ▸ | PYGL | P06737 | 1/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4110842 | 0.68 | MAPT (0.55) | MAPTTP53CYP1A2CYP2C9ALOX15 | |
| SCHEMBL4110835 | 0.68 | MAPT (0.55) | MAPTTP53CYP1A2CYP2C9ALOX15 | |
| SCHEMBL4110833 | 0.68 | MAPT (0.55) | MAPTTP53CYP1A2CYP2C9ALOX15 | |
| SCHEMBL10044117 | 0.68 | TP53 (0.79) | MAPTTP53CYP1A2CYP2C9ALOX15 | |
| SCHEMBL4118501 | 0.67 | GLA (0.43) | MAPTTP53CYP1A2CYP2C9ALOX15 | |
| SCHEMBL4118508 | 0.67 | GLA (0.43) | MAPTTP53CYP1A2CYP2C9ALOX15 | |
| SCHEMBL4118511 | 0.67 | GLA (0.43) | MAPTTP53CYP1A2CYP2C9ALOX15 | |
| SCHEMBL13776052 | 0.67 | CDYL2 (0.46) | MAPTTP53CYP1A2CYP2C9ALOX15 | |
| SCHEMBL8103029 | 0.65 | FDFT1 (0.39) | MAPTTP53CYP1A2CYP2C9ALOX15 | |
| SCHEMBL4112348 | 0.65 | CDYL2 (0.46) | MAPTTP53CYP1A2CYP2C9ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1939205-A1 | TRICYCLIC COMPOUND | Daiichi Sankyo Company, Limited (JP) | 2008-07-02 | — | — | EP | disclosed |