Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 8/20 | 0.47 |
| ▸ | PPARD | Q03181 | 6/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 2/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 7/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14146395 | 0.91 | PPARD (0.51) | PPARAPPARDPPARG | |
| SCHEMBL14146457 | 0.86 | PTPN1 (0.44) | PPARAPPARDRAB9AKDM4ENPC1 | |
| SCHEMBL4740499 | 0.83 | PPARA (0.55) | PPARAPPARDRAB9AKDM4ENPC1 | |
| SCHEMBL14146854 | 0.81 | PPARD (0.50) | PPARAPPARDPPARG | |
| SCHEMBL14146509 | 0.80 | PPARD (0.49) | PPARAPPARDPPARG | |
| SCHEMBL14146389 | 0.80 | PPARD (0.49) | PPARAPPARDPPARG | |
| SCHEMBL30007634 | 0.80 | PPARD (0.49) | PPARAPPARDPPARG | |
| SCHEMBL14146504 | 0.78 | PPARD (0.48) | PPARAPPARDPPARGPTPN1 | |
| SCHEMBL14146340 | 0.77 | PPARD (0.47) | PPARAPPARDPPARG | |
| SCHEMBL4738822 | 0.76 | PPARA (0.55) | PPARAPPARDRAB9AKDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008087367-A2 | SUBSTITUTED (PHENYLTHIAZOLYL)-PHENYL-PROPAN-1-ONE AND (PHENYLOXAZODYL)-PHENYL-PROPAN-1-ONE DERIVATIVES, PREPARATIONS AND USES OF SAME | GENFIT (FR) | 2008-07-24 | — | — | WO | disclosed |