Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMS | P04818 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14148150 | 0.82 | — | — | |
| SCHEMBL4737413 | 0.82 | TYMS (0.46) | TYMS | |
| SCHEMBL14148127 | 0.72 | FGFR1 (0.37) | — | |
| SCHEMBL13070957 | 0.70 | CASP1 (0.37) | — | |
| SCHEMBL4740750 | 0.64 | TYMS (0.46) | TYMS | |
| SCHEMBL13363063 | 0.62 | CASP1 (0.31) | — | |
| SCHEMBL883774 | 0.62 | CASP1 (0.59) | — | |
| SCHEMBL14345773 | 0.62 | CASP1 (0.31) | — | |
| SCHEMBL14148121 | 0.61 | TYMS (0.63) | TYMS | |
| SCHEMBL19417397 | 0.60 | SRD5A1 (0.53) | TYMS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008086158-A1 | BENZODIHYDROQUINAZOLINE AS PI3 KINASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2008-07-17 | — | — | WO | disclosed |