Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Adipic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 known ✓ | Q01959 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | HDAC11 | Q96DB2 | 6/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.34 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.34 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.34 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.34 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 4/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.33 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sebacic Acid SCHEMBL1537995 | 0.98 | HDAC11 (0.37) | LMNAHDAC11HDAC3HDAC4HDAC1 | |
| Succinic Acid SCHEMBL1414626 | 0.94 | CYP1A2 (0.33) | LMNAMAPK1TDP1ALDH1A1MEN1 | |
| SCHEMBL187691 | 0.88 | CYP1A2 (0.39) | MAPTTSHRMAPK1TDP1SMN1; SMN2 | |
| Ethylene Glycol SCHEMBL1924197 | 0.85 | CYP1A2 (0.34) | MAPTMAPK1ALDH1A1ALOX15HSD17B10 | |
| Adipic Acid SCHEMBL380003 | 0.76 | CYP1A2 (0.46) | LMNAHDAC11HDAC3HDAC4HDAC1 | |
| Sebacic Acid SCHEMBL1538072 | 0.74 | TSHR (0.48) | LMNAHDAC11HDAC3HDAC4HDAC1 | |
| Adipic Acid SCHEMBL382796 | 0.73 | CYP1A2 (0.43) | LMNAHDAC11HDAC3HDAC4HDAC1 | |
| SCHEMBL9282137 | 0.72 | — | — | |
| SCHEMBL5145610 | 0.71 | HCAR2 (0.40) | MAPTMAPK1ALDH1A1SLC22A6SLC22A8 | |
| Sebacic Acid SCHEMBL382438 | 0.71 | LMNA (0.44) | LMNAHDAC11HDAC3HDAC4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110269907-A1 | RESIN COMPOSITION AND MOLDED ARTICLE MADE THEREOF | TORAY INDUSTRIES, INC. (JP) | 2011-11-03 | — | — | US | disclosed |
| US-7999021-B2 | Resin composition and molded article made thereof | TORAY INDUSTRIES, INC. (JP) | 2011-08-16 | — | — | US | disclosed |
| EP-1792941-B1 | RESIN COMPOSITION AND MOLDED ARTICLE COMPRISING THE SAME | TORAY INDUSTRIES (JP) | 2011-05-18 | — | — | EP | disclosed |
| US-20110092622-A1 | NON-HALOGEN FLAME-RETARDANT SYNTHETIC RESIN COMPOSITION | ADEKA CORPORATION (JP) | 2011-04-21 | — | — | US | disclosed |
| US-20110071247-A1 | RESIN COMPOSITION AND MOLDED ARTICLE COMPRISING THE SAME | TORAY INDUSTRIES, INC. (JP) | 2011-03-24 | — | — | US | disclosed |
| EP-2295501-A1 | NON-HALOGEN FLAME-RETARDANT SYNTHETIC RESIN COMPOSITION | Adeka Corporation (JP) | 2011-03-16 | — | — | EP | disclosed |
| US-7863382-B2 | Resin composition and molded article comprising the same | Toray Industriés, Inc. (JP) | 2011-01-04 | — | — | US | disclosed |