Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Adipic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 known ✓ | Q01959 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.42 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.42 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.42 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sebacic Acid SCHEMBL1538072 | 0.98 | TSHR (0.48) | CYP1A2LMNANFKB1TSHRPMP22 | |
| Adipic Acid SCHEMBL382796 | 0.92 | CYP1A2 (0.43) | CYP1A2LMNANFKB1TSHRPMP22 | |
| Succinic Acid SCHEMBL1414629 | 0.91 | CYP1A2 (0.50) | CYP1A2LMNATSHRMAPTSMN1; SMN2 | |
| Sebacic Acid SCHEMBL382438 | 0.90 | LMNA (0.44) | CYP1A2LMNANFKB1TSHRPMP22 | |
| SCHEMBL21688 | 0.84 | CYP1A2 (0.63) | CYP1A2TSHRHDAC8MAPTSMN1; SMN2 | |
| SCHEMBL29769278 | 0.84 | CYP1A2 (0.63) | CYP1A2TSHRHDAC8MAPTSMN1; SMN2 | |
| Succinic Acid SCHEMBL1537986 | 0.83 | CYP1A2 (0.46) | CYP1A2LMNAKDM4ECYP2D6 | |
| Adipic Acid SCHEMBL1538021 | 0.83 | ALOX15 (0.40) | LMNATSHRHDAC3HDAC4HDAC1 | |
| Hydrochloric Acid SCHEMBL607308 | 0.82 | CYP1A2 (0.60) | CYP1A2TSHRHDAC8MAPTSMN1; SMN2 | |
| Ethylene Glycol SCHEMBL1325969 | 0.80 | CYP1A2 (0.52) | CYP1A2TSHRMAPTSMN1; SMN2SLC22A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0124800-B1 | EPOXY RESIN LAMINATE FOR A PRINTED-CIRCUIT BOARD | HÜLS TROISDORF AKTIENGESELLSCHAFT (DE) | 1990-07-18 | — | — | EP | claimed |
| US-20120028047-A1 | Fiber reinforced resin composition, molding material, and method for producing fiber reinforced resin composition | TORAY INDUSTRIES, INC. (JP) | 2012-02-02 | — | — | US | disclosed |
| EP-2410021-A1 | FIBER REINFORCED RESIN COMPOSITION, MOLDING MATERIAL, AND METHOD FOR PRODUCING FIBER REINFORCED RESIN COMPOSITION | Toray Industries, Inc. (JP) | 2012-01-25 | — | — | EP | disclosed |
| US-20110269907-A1 | RESIN COMPOSITION AND MOLDED ARTICLE MADE THEREOF | TORAY INDUSTRIES, INC. (JP) | 2011-11-03 | — | — | US | disclosed |
| EP-2380883-A1 | CYCLIC CARBODIIMIDE COMPOUNDS | Teijin Limited (JP) | 2011-10-26 | — | — | EP | disclosed |
| US-20110251384-A1 | CYCLIC CARBODIIMIDE COMPOUNDS | TEIJIN LIMITED (JP) | 2011-10-13 | — | — | US | disclosed |
| EP-2374833-A1 | METHOD FOR USING CYCLIC CARBODIMIDE | Teijin Limited (JP) | 2011-10-12 | — | — | EP | disclosed |
| US-8030382-B2 | Polylactic acid composition | TEIJIN LIMITED (JP) | 2011-10-04 | — | — | US | disclosed |
| US-20110237755-A1 | METHOD OF USING A CYCLIC CARBODIIMIDE | TEIJIN LIMITED (JP) | 2011-09-29 | — | — | US | disclosed |
| US-7999021-B2 | Resin composition and molded article made thereof | TORAY INDUSTRIES, INC. (JP) | 2011-08-16 | — | — | US | disclosed |
| US-7960473-B2 | Thermoplastic resin composition, production method thereof, and molded article | TORAY INDUSTRIES, INC. (JP) | 2011-06-14 | — | — | US | disclosed |
| US-7960464-B2 | Thermoplastic resin composition and molded article | TORAY INDUSTRIES, INC. (JP) | 2011-06-14 | — | — | US | disclosed |
| EP-1792941-B1 | RESIN COMPOSITION AND MOLDED ARTICLE COMPRISING THE SAME | TORAY INDUSTRIES (JP) | 2011-05-18 | — | — | EP | disclosed |
| US-20110092622-A1 | NON-HALOGEN FLAME-RETARDANT SYNTHETIC RESIN COMPOSITION | ADEKA CORPORATION (JP) | 2011-04-21 | — | — | US | disclosed |
| US-20110071247-A1 | RESIN COMPOSITION AND MOLDED ARTICLE COMPRISING THE SAME | TORAY INDUSTRIES, INC. (JP) | 2011-03-24 | — | — | US | disclosed |
| US-20110021707-A1 | PROCESS FOR PRODUCING THERMOPLASTIC RESIN COMPOSITION | TORAY INDUSTRIES, INC. (JP) | 2011-01-27 | — | — | US | disclosed |
| EP-2270073-A1 | PROCESS FOR PRODUCING THERMOPLASTIC RESIN COMPOSITION | Toray Industries, Inc. (JP) | 2011-01-05 | — | — | EP | disclosed |
| US-7863382-B2 | Resin composition and molded article comprising the same | Toray Industriés, Inc. (JP) | 2011-01-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110251384-A1 | CYCLIC CARBODIIMIDE COMPOUNDS | APEX1, LIG4, EPB41 | SLC6A3 4456/4885CYP1A2 4408/4885LMNA 3037/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.