Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 2/20 | 0.43 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | MMP8 | P22894 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16985332 | 0.84 | CYP4F2 (0.45) | CYP4F2CYP4A11KMT2AALDH1A1FGFR3 | |
| SCHEMBL29427420 | 0.81 | ABCB11 (0.44) | CYP4F2CYP4A11KMT2AALDH1A1FGFR3 | |
| SCHEMBL16423620 | 0.81 | CYP4F2 (0.43) | CYP4F2CYP4A11KMT2AALDH1A1FGFR3 | |
| SCHEMBL4076690 | 0.81 | CYP4F2 (0.43) | CYP4F2CYP4A11KMT2AALDH1A1FGFR3 | |
| SCHEMBL13412138 | 0.81 | CYP4F2 (0.43) | CYP4F2CYP4A11ALDH1A1FGFR3KDR | |
| SCHEMBL24627322 | 0.79 | CYP4F2 (0.41) | CYP4F2CYP4A11KMT2AALDH1A1FGFR3 | |
| SCHEMBL15895031 | 0.77 | MAPT (0.42) | CYP4F2CYP4A11KMT2AALDH1A1CYP3A4 | |
| SCHEMBL25380972 | 0.77 | FGFR3 (0.47) | CYP4F2CYP4A11KMT2AALDH1A1FGFR3 | |
| SCHEMBL22070525 | 0.75 | CYP4F2 (0.58) | CYP4F2CYP4A11KMT2AALDH1A1FGFR3 | |
| SCHEMBL19006417 | 0.71 | CYP4F2 (0.45) | CYP4F2CYP4A11KMT2AALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008088881-A1 | KINASE INHIBITOR COMPOUNDS | XCOVERY, INC. (US) | 2008-07-24 | — | — | WO | disclosed |