Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | ALB | P02768 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | ADA | P00813 | 2/20 | 0.39 |
| ▸ | DNMT3B | Q9UBC3 | 1/20 | 0.39 |
| ▸ | ABL1 | P00519 | 3/20 | 0.37 |
| ▸ | RIN1 | Q13671 | 3/20 | 0.37 |
| ▸ | FDPS | P14324 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8783994 | 1.00 | ALDH1A1 (0.53) | ALDH1A1LMNAALBMAPK1CYP1A2 | |
| SCHEMBL21393029 | 0.88 | ALDH1A1 (0.41) | ALDH1A1LMNAALBMAPK1CYP1A2 | |
| SCHEMBL22643725 | 0.84 | ALDH1A1 (0.39) | ALDH1A1LMNAALBMAPK1CYP1A2 | |
| SCHEMBL14149655 | 0.82 | ALDH1A1 (0.40) | ALDH1A1LMNAALBMAPK1CYP1A2 | |
| SCHEMBL21393030 | 0.82 | ALDH1A1 (0.40) | ALDH1A1LMNAALBMAPK1CYP1A2 | |
| SCHEMBL20324736 | 0.82 | FDPS (0.40) | ALDH1A1LMNAALBMAPK1FDPS | |
| SCHEMBL21427363 | 0.82 | ALDH1A1 (0.40) | ALDH1A1LMNAALBMAPK1CYP1A2 | |
| SCHEMBL21393211 | 0.81 | ALDH1A1 (0.40) | ALDH1A1LMNAALBMAPK1CYP1A2 | |
| SCHEMBL24276633 | 0.81 | ALDH1A1 (0.39) | ALDH1A1LMNAALBMAPK1DNMT3B | |
| SCHEMBL19391966 | 0.81 | ALDH1A1 (0.38) | ALDH1A1LMNAALBMAPK1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020016782-A1 | CYCLIC DINUCLEOTIDES AS STING AGONISTS | JANSSEN BIOTECH, INC. (US) | 2020-01-23 | — | — | WO | disclosed |
| US-7393954-B2 | Process for the production of pentostatin aglycone and pentostatin | RELIABLE BIOPHARMACEUTICAL CORPORATION (US) | 2008-07-01 | — | — | US | disclosed |