Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | CA9 | Q16790 | 2/20 | 0.35 |
| ▸ | STS | P08842 | 5/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.34 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.34 |
| ▸ | SHBG | P04278 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | THPO | P40225 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10356258 | 0.80 | HSD17B10 (0.52) | CA2CA9STSCYP3A4MEN1 | |
| SCHEMBL8775736 | 0.80 | HSD17B10 (0.52) | CA2CA9STSCYP3A4MEN1 | |
| SCHEMBL8987888 | 0.67 | — | — | |
| SCHEMBL8970922 | 0.64 | AKR1C3 (0.42) | STSCYP3A4MEN1LMNAKMT2A | |
| SCHEMBL13240148 | 0.61 | STS (0.60) | CA2CA9STSCYP3A4MEN1 | |
| SCHEMBL6130971 | 0.61 | CA2 (0.58) | CA2CA9STSCYP3A4MEN1 | |
| SCHEMBL9111396 | 0.60 | AKR1C3 (0.81) | CA2CA9STSCYP3A4CYP19A1 | |
| SCHEMBL10523535 | 0.59 | ESR1 (0.69) | STSCYP3A4CYP19A1MEN1LMNA | |
| SCHEMBL13645679 | 0.59 | HSD17B10 (0.49) | CA2CA9STSCYP3A4MEN1 | |
| SCHEMBL10524367 | 0.58 | CYP3A4 (0.52) | CA2STSCYP3A4MEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2367808-A2 | PROGESTATIONAL 3-(6,6-ETHYLENE-17b-HYDROXY-3-OXO-17a-PREGNA-4-ENE-17a-YL) PROPIONIC ACID g-LACTONES | Evestra, Inc. (US) | 2011-09-28 | — | — | EP | disclosed |
| EP-2293779-A1 | ORAL CONTRACEPTIVE DOSAGE FORMS COMPRISING A PROGESTOGEN DISPERSED IN AN ENTERIC POLYMER AND FURTHER COMPRISING AN ESTROGEN | Evestra, Inc. (US) | 2011-03-16 | — | — | EP | disclosed |
| WO-2010068500-A2 | PROGESTATIONAL 3-(6,6-ETHYLENE-17b-HYDROXY-3-OXO-17a-PREGNA-4-ENE-17a -YL) PROPIONIC ACID g-LACTONES | EVESTRA, INC. (US) | 2010-06-17 | — | — | WO | disclosed |
| WO-2009132208-A1 | ORAL CONTRACEPTIVE DOSAGE FORMS COMPRISING A PROGESTOGEN DISPERSED IN AN ENTERIC POLYMER AND FURTHER COMPRISING AN ESTROGEN | EVESTRA, INC. (US) | 2009-10-29 | — | — | WO | disclosed |