SCHEMBL14152012

SCHEMBL14152012

Nc1ccc(CCOC(=O)/C=C/c2ccc(OC(=O)c3ccc(OCCCC(F)(F)C(F)(F)F)c(OCCCC(F)(F)C(F)(F)F)c3)cc2)c(N)c1

nearest known ligand 0.38

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
MET P08581 10/20 0.38
ALOX5 P09917 2/20 0.38
MAPT P10636 2/20 0.35
FDPS P14324 1/20 0.35
LMNA P02545 1/20 0.35
MAPK1 P28482 1/20 0.35
CA12 O43570 1/20 0.34
CA1 P00915 1/20 0.34
CA2 P00918 1/20 0.34
CA4 P22748 1/20 0.34
CA9 Q16790 1/20 0.34
KDM4E B2RXH2 1/20 0.34
TTR P02766 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14152013 1.00 MET (0.38) METALOX5MAPTFDPSLMNA
SCHEMBL2142251 0.96 MET (0.42) METALOX5MAPTFDPSLMNA
SCHEMBL1564827 0.94 MET (0.37) METALOX5MAPTFDPSLMNA
SCHEMBL678510 0.92 MET (0.38) METALOX5MAPTLMNACA12
SCHEMBL15772156 0.92 MET (0.38) METALOX5MAPTLMNACA12
SCHEMBL1565064 0.91 MET (0.42) METALOX5MAPTFDPSLMNA
SCHEMBL2140305 0.90 MET (0.38) METALOX5MAPTLMNACA12
SCHEMBL1563983 0.88 MET (0.42) METALOX5MAPTFDPSLMNA
SCHEMBL2136678 0.88 MET (0.38) METALOX5MAPTLMNACA12
SCHEMBL1564818 0.87 ALOX5 (0.37) METALOX5CA12CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2534191-B1 PHOTOALIGNING MATERIAL WITH LATERAL SUBSTITUTION ROLIC TECH AG (CH) 2020-04-15 EP disclosed
US-20120316317-A1 PHOTOALIGNING MATERIAL WITH LATERAL SUBSTITUTION ROLIC AG (CH) 2012-12-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120316317-A1 PHOTOALIGNING MATERIAL WITH LATERAL SUBSTITUTION LATS1, LATS2, LCP1 MET 3618/4885ALOX5 524/4885MAPT 440/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.