SCHEMBL1415253

SCHEMBL1415253

NC(=O)c1cccc(C=Cc2ccccc2)c1C(N)=O

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SIRT2 Q8IXJ6 1/20 0.51
TRPA1 O75762 1/20 0.46
MAPT P10636 5/20 0.45
KDM4E B2RXH2 4/20 0.45
ALDH1A1 P00352 4/20 0.45
LMNA P02545 3/20 0.45
HPGD P15428 3/20 0.45
NFE2L2 Q16236 1/20 0.42
SIRT1 Q96EB6 1/20 0.42
SMO Q99835 1/20 0.41
SMN1; SMN2 Q16637 4/20 0.41
MEN1 O00255 3/20 0.41
NPC1 O15118 3/20 0.41
RAB9A P51151 3/20 0.41
KMT2A Q03164 3/20 0.41
CYP1A2 P05177 2/20 0.41
CYP2C19 P33261 2/20 0.41
CAPN1 P07384 1/20 0.41
CYP3A4 P08684 1/20 0.41
BCAT2 O15382 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31678976 0.86 SIRT2 (0.57) SIRT2TRPA1MAPTKDM4EALDH1A1
SCHEMBL3639133 0.86 SIRT2 (0.57) SIRT2TRPA1MAPTKDM4EALDH1A1
SCHEMBL2037764 0.86 SIRT2 (0.57) SIRT2TRPA1MAPTKDM4EALDH1A1
SCHEMBL7928539 0.83 TRPA1 (0.59) SIRT2TRPA1MAPTNFE2L2CYP2C19
SCHEMBL28053289 0.82 SIRT2 (0.50) SIRT2TRPA1MAPTKDM4EALDH1A1
SCHEMBL114584 0.79 PTPN1 (0.49) TRPA1MAPTALDH1A1LMNANFE2L2
Hydrochloric Acid SCHEMBL894924 0.78 PTPN1 (0.47) TRPA1MAPTALDH1A1LMNANFE2L2
Hydrochloric Acid SCHEMBL9622267 0.78 PTPN1 (0.47) TRPA1MAPTALDH1A1LMNANFE2L2
SCHEMBL9464203 0.77 TRPA1 (0.46) SIRT2TRPA1ALDH1A1HPGDNFE2L2
SCHEMBL7751066 0.77 TRPA1 (0.46) TRPA1MAPTALDH1A1LMNANFE2L2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 127 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118707642-A High-color-gamut backlight module and preparation method thereof 湖南壹鑫科技有限公司 2024-09-27 CN claimed
CN-118707642-A High-color-gamut backlight module and preparation method thereof 湖南壹鑫科技有限公司 2024-09-27 CN disclosed
EP-1818417-B1 Nanoparticles having oligonucleotides attached thereto and uses therefor NANOSPHERE INC (US) 2014-02-12 EP disclosed
US-8323888-B2 Nanoparticles having oligonucleotides attached thereto and uses therefor NANOSPHERE, INC. (US) 2012-12-04 US disclosed
EP-1294930-B1 NANOPARTICLES HAVING OLIGONUCLEOTIDES ATTACHED THERETO AND USES THEREFOR NANOSPHERE INC (US) 2011-03-30 EP disclosed
EP-1198591-B1 NANOPARTICLES HAVING OLIGONUCLEOTIDES ATTACHED THERETO AND USES THEREFOR NANOSPHERE INC (US) 2011-03-16 EP disclosed
EP-1301625-B1 NANOPARTICLES HAVING OLIGONUCLEOTIDES ATTACHED THERETO AND USES THEREFOR NANOSPHERE INC (US) 2010-11-03 EP disclosed
WO-2001051665-A9 NANOPARTICLES HAVING OLIGONUCLEOTIDES ATTACHED THERETO AND USES THEREFOR NANOSPHERE INC. (US) 2010-09-23 WO disclosed
US-20090325812-A1 Nanoparticles having oligonucleotides attached thereto and uses therefor NANOSPHERE, INC. (US) 2009-12-31 US disclosed
EP-1198591-A4 NANOPARTICLES HAVING OLIGONUCLEOTIDES ATTACHED THERETO AND USES THEREFOR NANOSPHERE INC (US) 2007-10-24 EP disclosed
US-6010907-A TRANSFORMING TARGET DNA SEQUENCES KIMERAGEN, INC. (US) 2000-01-04 US disclosed
US-6004804-A 3'-EXONUCLEASE PROTECTED DUPLEX MUTATIONAL VECTORS; USED TO MAKE SPECIFIC GENETIC ALTERATIONS IN THE GENOME AND IN PLASMIDS OF TARGET PROKARYOTIC CELLS KIMERAGEN, INC. (US) 1999-12-21 US disclosed
WO-1999058723-A1 HETERODUPLEX MUTATIONAL VECTORS AND USE THEREOF IN BACTERIA KIMERAGEN, INC. (US) 1999-11-18 WO disclosed
WO-1999058702-A1 CELL-FREE CHIMERAPLASTY AND EUKARYOTIC USE OF HETERODUPLEX MUTATIONAL VECTORS KIMERAGEN, INC. (US) 1999-11-18 WO disclosed
WO-1999040789-A1 METHODS AND COMPOUNDS FOR THE GENETIC TREATMENT OF HYPERLIPIDEMIA REGENTS OF THE UNIVERSITY OF MINNESOTA (US) 1999-08-19 WO disclosed
EP-0918885-A1 NANOPARTICLES HAVING OLIGONUCLEOTIDES ATTACHED THERETO AND USES THEREFOR Nanosphere LLC (US) 1999-06-02 EP disclosed
US-5780613-A DISPLACING 5' DISPLACEABLE GROUP BY A 3' THIOPHOSPHORYL GROUP TO FORM INTERNUCLEOSIDE LINKAGE NORTHWESTERN UNIVERSITY (US) 1998-07-14 US disclosed
WO-1998004740-A9 NANOPARTICLES HAVING OLIGONUCLEOTIDES ATTACHED THERETO AND USES THEREFOR 1998-04-30 WO disclosed
WO-1998004740-A1 NANOPARTICLES HAVING OLIGONUCLEOTIDES ATTACHED THERETO AND USES THEREFOR NANOSPHERE LLC (US) 1998-02-05 WO disclosed
WO-1997005284-A1 COVALENT LOCK FOR SELF-ASSEMBLED OLIGONUCLEOTIDE CONSTRUCTS NORTHWESTERN UNIVERSITY (US) 1997-02-13 WO disclosed