Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.50 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.41 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.41 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | TNKS | O95271 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3639133 | 0.84 | SIRT2 (0.57) | SIRT2TRPA1MAPTALDH1A1KDM4E | |
| SCHEMBL2037764 | 0.84 | SIRT2 (0.57) | SIRT2TRPA1MAPTALDH1A1KDM4E | |
| SCHEMBL31678976 | 0.84 | SIRT2 (0.57) | SIRT2TRPA1MAPTALDH1A1KDM4E | |
| SCHEMBL1415253 | 0.82 | SIRT2 (0.51) | SIRT2TRPA1MAPTALDH1A1KDM4E | |
| SCHEMBL1415250 | 0.74 | ALDH1A1 (0.54) | SIRT2MAPTALDH1A1KDM4ELMNA | |
| SCHEMBL27486058 | 0.74 | KDM4E (0.52) | MAPTALDH1A1KDM4EHPGDSIRT1 | |
| SCHEMBL10454313 | 0.73 | NFE2L2 (0.50) | TRPA1SIGMAR1NFE2L2 | |
| SCHEMBL28410501 | 0.73 | NFE2L2 (0.50) | TRPA1SIGMAR1NFE2L2 | |
| SCHEMBL2291774 | 0.73 | GRIK1 (0.58) | TRPA1MAPTALDH1A1LMNANFE2L2 | |
| SCHEMBL29542528 | 0.73 | GRIK1 (0.58) | TRPA1MAPTALDH1A1LMNANFE2L2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105294597-A | Benzothiazine derivative, and synthetic method and application thereof | UNIV EAST CHINA NORMAL | 2016-02-03 | — | — | CN | claimed |
| CN-105294597-A | Benzothiazine derivative, and synthetic method and application thereof | UNIV EAST CHINA NORMAL | 2016-02-03 | — | — | CN | disclosed |