Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | HTR1D | P28221 | 5/20 | 0.43 |
| ▸ | HTR1B | P28222 | 5/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | CD38 | P28907 | 1/20 | 0.41 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.40 |
| ▸ | ERN1 | O75460 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9979919 | 0.98 | NR4A2 (0.51) | NR4A2L3MBTL1KCNH2HTR1DHTR1B | |
| SCHEMBL9979918 | 0.88 | NR4A2 (0.43) | NR4A2L3MBTL1KCNH2HTR1DHTR1B | |
| SCHEMBL20987442 | 0.86 | NR4A2 (0.46) | NR4A2L3MBTL1CD38CHEK1KDM4E | |
| SCHEMBL15747195 | 0.82 | KDM4E (0.44) | NR4A2KDM4EALDH1A1 | |
| SCHEMBL12943080 | 0.79 | NR4A2 (0.38) | NR4A2L3MBTL1KCNH2HTR1DHTR1B | |
| SCHEMBL14107130 | 0.77 | KDM4E (0.46) | NR4A2KDM4EALDH1A1 | |
| SCHEMBL20987436 | 0.76 | CNR2 (0.47) | NR4A2KDM4EALDH1A1 | |
| SCHEMBL28215696 | 0.76 | NR4A2 (0.46) | NR4A2KCNH2HTR1DHTR1BKDM4E | |
| SCHEMBL12419782 | 0.75 | GPR3 (0.64) | L3MBTL1KDM4ENPC1ALDH1A1RAB9A | |
| SCHEMBL31223938 | 0.75 | NR4A2 (0.46) | NR4A2L3MBTL1KCNH2CD38CHEK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7402681-B2 | Compound with indolocarbazole moieties and devices containing such compound | XEROX CORPORATION (US) | 2008-07-22 | — | — | US | disclosed |