Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 1/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.44 |
| ▸ | HTR1D | P28221 | 5/20 | 0.43 |
| ▸ | HTR1B | P28222 | 5/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | CD38 | P28907 | 1/20 | 0.42 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.40 |
| ▸ | ERN1 | O75460 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14153340 | 0.98 | NR4A2 (0.50) | NR4A2KCNH2L3MBTL1HTR1DHTR1B | |
| SCHEMBL9979918 | 0.90 | NR4A2 (0.43) | NR4A2KCNH2L3MBTL1HTR1DHTR1B | |
| SCHEMBL20987442 | 0.85 | NR4A2 (0.46) | NR4A2L3MBTL1CD38CHEK1KDM4E | |
| SCHEMBL15747195 | 0.83 | KDM4E (0.44) | NR4A2KDM4EALDH1A1 | |
| SCHEMBL12943080 | 0.81 | NR4A2 (0.38) | NR4A2KCNH2L3MBTL1HTR1DHTR1B | |
| SCHEMBL20987436 | 0.77 | CNR2 (0.47) | NR4A2KDM4EALDH1A1 | |
| SCHEMBL28215696 | 0.77 | NR4A2 (0.46) | NR4A2KCNH2HTR1DHTR1BKDM4E | |
| SCHEMBL31223938 | 0.76 | NR4A2 (0.46) | NR4A2KCNH2L3MBTL1CD38CHEK1 | |
| SCHEMBL925258 | 0.76 | KDM4E (0.47) | NR4A2KDM4EALDH1A1 | |
| SCHEMBL27964962 | 0.75 | KDM4E (0.46) | NR4A2KCNH2L3MBTL1HTR1DHTR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120157689-A1 | SUBSTITUTED INDOLOCARBAZOLES | XEROX CORPORATION (US) | 2012-06-21 | — | — | US | disclosed |
| US-8110690-B2 | Substituted indolocarbazoles | XEROX CORPORATION (US) | 2012-02-07 | — | — | US | disclosed |
| US-8003807-B2 | organic thin film transistor with a semiconductor layer including the small molecule having didodecylindolo[3,2-b]carbazole groups | XEROX CORPORATION (US) | 2011-08-23 | — | — | US | disclosed |
| US-7829727-B2 | Device containing compound having indolocarbazole moiety and divalent linkage | XEROX CORPORATION (US) | 2010-11-09 | — | — | US | disclosed |
| US-20100230670-A1 | DEVICE CONTAINING COMPOUND HAVING INDOLOCARBAZOLE MOIETY AND DIVALENT LINKAGE | XEROX CORPORATION (US) | 2010-09-16 | — | — | US | disclosed |
| US-7528261-B2 | Small molecule compound having indolocarbazole moiety and divalent linkage | XEROX CORPORATION (US) | 2009-05-05 | — | — | US | disclosed |
| US-20090036689-A1 | SUBSTITUTED INDOLOCARBAZOLES | XEROX CORPORATION (US) | 2009-02-05 | — | — | US | disclosed |
| US-7456424-B2 | Thin film transistors including indolocarbozoles | XEROX CORPORATION (US) | 2008-11-25 | — | — | US | disclosed |
| US-20080207917-A1 | POLYMER HAVING INDOLOCARBAZOLE MOIETY AND DIVALENT LINKAGE | XEROX CORPORATION (US) | 2008-08-28 | — | — | US | disclosed |
| US-7396852-B2 | Compound having indolocarbazole moiety and divalent linkage | XEROX CORPORATION (US) | 2008-07-08 | — | — | US | disclosed |
| US-20080103314-A1 | SMALL MOLECULE COMPOUND HAVING INDOLOCARBAZOLE MOIETY AND DIVALENT LINKAGE | XEROX CORPORATION (US) | 2008-05-01 | — | — | US | disclosed |
| US-20070112167-A1 | Device containing compound having indolocarbazole moiety and divalent linkage | XEROX CORPORATION | 2007-05-17 | — | — | US | disclosed |
| US-20070112172-A1 | Compound having indolocarbazole moiety and divalent linkage | XEROX CORPORATION | 2007-05-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090036689-A1 | SUBSTITUTED INDOLOCARBAZOLES | HTR3C, HTR3A, AANAT | NR4A2 1210/4885KCNH2 2236/4885L3MBTL1 1311/4885 |
| US-20070112172-A1 | Compound having indolocarbazole moiety and divalent linkage | INMT, IDO2, GRIN2C | NR4A2 1476/4885KCNH2 619/4885L3MBTL1 2177/4885 |
| US-20080103314-A1 | SMALL MOLECULE COMPOUND HAVING INDOLOCARBAZOLE MOIETY AND DIVALENT LINKAGE | SLC43A1, SLC7A5, KCNN2 | NR4A2 2187/4885KCNH2 935/4885L3MBTL1 3134/4885 |
| US-20100230670-A1 | DEVICE CONTAINING COMPOUND HAVING INDOLOCARBAZOLE MOIETY AND DIVALENT LINKAGE | BRD4, BICRA, INMT | NR4A2 1948/4885KCNH2 75/4885L3MBTL1 1990/4885 |
| US-20080207917-A1 | POLYMER HAVING INDOLOCARBAZOLE MOIETY AND DIVALENT LINKAGE | SGTA, MTCL3, SMC3 | NR4A2 2869/4885KCNH2 2585/4885L3MBTL1 1538/4885 |
| US-20120157689-A1 | SUBSTITUTED INDOLOCARBAZOLES | HTR3C, HTR3A, AANAT | NR4A2 1210/4885KCNH2 2236/4885L3MBTL1 1311/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.