Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 5/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | RHOA | P61586 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | PROKR1 | Q8TCW9 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1415645 | 0.85 | KDM4E (0.49) | TYRALDH1A1L3MBTL1ADORA3RAB9A | |
| SCHEMBL1415600 | 0.85 | KDM4E (0.49) | TYRALDH1A1L3MBTL1ADORA3RAB9A | |
| SCHEMBL1415639 | 0.85 | KDM4E (0.49) | TYRALDH1A1L3MBTL1ADORA3RAB9A | |
| SCHEMBL1415476 | 0.85 | KDM4E (0.49) | TYRALDH1A1L3MBTL1ADORA3RAB9A | |
| SCHEMBL1415875 | 0.85 | TYR (0.43) | TYRALDH1A1L3MBTL1ADORA3RAB9A | |
| SCHEMBL1415372 | 0.85 | TYR (0.43) | TYRALDH1A1L3MBTL1ADORA3RAB9A | |
| SCHEMBL1415531 | 0.84 | TYR (0.42) | TYRALDH1A1POLBMEN1KMT2A | |
| SCHEMBL1415206 | 0.84 | REV1 (0.50) | TYRALDH1A1RAB9APOLBMEN1 | |
| SCHEMBL1415414 | 0.84 | ALDH1A1 (0.45) | TYRALDH1A1L3MBTL1ADORA3RAB9A | |
| SCHEMBL1415297 | 0.83 | TYR (0.42) | TYRALDH1A1L3MBTL1ADORA3RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1807421-B1 | 2-AMIDO-4-PHENYLTHIAZOLE DERIVATIVES, THE PREPARATION AND THE THERAPEUTIC USE THEREOF | SANOFI AVENTIS (FR) | 2011-03-16 | — | — | EP | claimed |