Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | NPY5R | Q15761 | 6/20 | 0.51 |
| ▸ | SMPD3 | Q9NY59 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.42 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.42 |
| ▸ | TNKS | O95271 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | WNT3A | P56704 | 1/20 | 0.41 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.41 |
| ▸ | RAF1 | P04049 | 1/20 | 0.41 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.41 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6861541 | 0.96 | KMT2A (0.57) | KMT2AL3MBTL1NPY5RSMPD3KDM4E | |
| SCHEMBL15913449 | 0.86 | KMT2A (0.44) | KMT2AL3MBTL1NPY5RSMPD3KDM4E | |
| SCHEMBL25220187 | 0.83 | SMPD3 (0.49) | KMT2AL3MBTL1NPY5RSMPD3KDM4E | |
| SCHEMBL14153752 | 0.83 | SMPD3 (0.49) | KMT2AL3MBTL1NPY5RSMPD3KDM4E | |
| SCHEMBL11844688 | 0.79 | TNKS2 (0.50) | KMT2AL3MBTL1SMPD3TNKSPARP1 | |
| SCHEMBL8319716 | 0.75 | PDCD1 (0.53) | KMT2AL3MBTL1NPY5RKDM4EALDH1A1 | |
| SCHEMBL12492799 | 0.75 | PDCD1 (0.68) | KMT2AL3MBTL1NPY5RKDM4EALDH1A1 | |
| SCHEMBL25120538 | 0.73 | NPY5R (0.39) | KMT2AL3MBTL1NPY5RSMPD3KDM4E | |
| SCHEMBL22408471 | 0.73 | ALDH1A1 (0.49) | L3MBTL1NPY5RSMPD3KDM4EALDH1A1 | |
| SCHEMBL1032502 | 0.73 | TNKS2 (0.68) | KMT2AL3MBTL1KDM4EALDH1A1TNKS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012162635-A1 | METABOTROPIC GLUTAMATE RECEPTORS 5 MODULATORS AND METHODS OF USE THEREOF | SUNOVION PHARMACEUTICALS INC. (US) | 2012-11-29 | — | — | WO | disclosed |