Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADK | P55263 | 1/20 | 0.46 |
| ▸ | PRMT5 | O14744 | 9/20 | 0.45 |
| ▸ | WDR77 | Q9BQA1 | 9/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.44 |
| ▸ | METTL3 | Q86U44 | 1/20 | 0.41 |
| ▸ | METTL14 | Q9HCE5 | 1/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.41 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14154376 | 0.88 | ADK (0.43) | ADKPRMT5WDR77ADORA3METTL3 | |
| SCHEMBL14154373 | 0.88 | PRMT5 (0.49) | ADKPRMT5WDR77ADORA3METTL3 | |
| SCHEMBL14089358 | 0.86 | ADORA3 (0.57) | ADKPRMT5WDR77ADORA3METTL3 | |
| SCHEMBL13598817 | 0.86 | ADORA3 (0.57) | ADKPRMT5WDR77ADORA3METTL3 | |
| SCHEMBL4430766 | 0.86 | ADORA3 (0.57) | ADKPRMT5WDR77ADORA3METTL3 | |
| SCHEMBL13598664 | 0.86 | ADORA3 (0.57) | ADKPRMT5WDR77ADORA3METTL3 | |
| SCHEMBL14154248 | 0.85 | ADK (0.47) | ADKPRMT5WDR77ADORA3METTL3 | |
| SCHEMBL14154308 | 0.85 | PRMT5 (0.48) | ADKPRMT5WDR77ADORA3METTL3 | |
| SCHEMBL474831 | 0.85 | PRMT5 (0.54) | ADKPRMT5WDR77METTL3ADORA2A | |
| SCHEMBL12150851 | 0.85 | PRMT5 (0.54) | ADKPRMT5WDR77METTL3ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7405204-B2 | Nucleoside compounds for treating viral infections | GENELABS TECHNOLOGIES, INC. (US) | 2008-07-29 | — | — | US | disclosed |