Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOD1 | Q9Y239 | 3/20 | 0.45 |
| ▸ | FOLH1 | Q04609 | 8/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MME | P08473 | 1/20 | 0.42 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | NAALAD2 | Q9Y3Q0 | 4/20 | 0.39 |
| ▸ | RIMKLA | Q8IXN7 | 1/20 | 0.39 |
| ▸ | GNPAT | O15228 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2487239 | 0.83 | NOD1 (0.51) | NOD1FOLH1MMEPIN1CYP2C9 | |
| SCHEMBL2487237 | 0.83 | NOD1 (0.51) | NOD1FOLH1MMEPIN1CYP2C9 | |
| SCHEMBL19586695 | 0.82 | FOLH1 (0.42) | NOD1FOLH1ALDH1A1MMEMEN1 | |
| SCHEMBL19586694 | 0.82 | FOLH1 (0.42) | NOD1FOLH1ALDH1A1MMEMEN1 | |
| SCHEMBL4186349 | 0.82 | ALDH1A1 (0.64) | FOLH1ALDH1A1MMEMEN1LMNA | |
| SCHEMBL4186354 | 0.82 | ALDH1A1 (0.64) | FOLH1ALDH1A1MMEMEN1LMNA | |
| SCHEMBL3498357 | 0.82 | NOD1 (0.46) | NOD1FOLH1MMEPIN1CYP2C9 | |
| SCHEMBL15857620 | 0.82 | ALDH1A1 (0.64) | FOLH1ALDH1A1MMEMEN1LMNA | |
| SCHEMBL3498364 | 0.82 | NOD1 (0.46) | NOD1FOLH1MMEPIN1CYP2C9 | |
| SCHEMBL6668178 | 0.80 | NOD1 (0.62) | NOD1GNPAT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2293845-A1 | DEPSIPEPTIDES AND THEIR THERAPEUTIC USE | Karus Therapeutics Limited (GB) | 2011-03-16 | — | — | EP | disclosed |
| WO-2009141657-A1 | DEPSIPEPTIDES AND THEIR THERAPEUTIC USE | KARUS THERAPEUTICS LIMITED (GB) | 2009-11-26 | — | — | WO | disclosed |