Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | IKBKB | O14920 | 2/20 | 0.48 |
| ▸ | PARP1 | P09874 | 3/20 | 0.45 |
| ▸ | CA1 | P00915 | 2/20 | 0.45 |
| ▸ | CA2 | P00918 | 2/20 | 0.45 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.45 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.45 |
| ▸ | PARP4 | Q9UKK3 | 1/20 | 0.45 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.43 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14154660 | 0.82 | CA1 (0.55) | IKBKBCA1CA2CASP1MAP4K4 | |
| SCHEMBL14113347 | 0.82 | TDP1 (0.52) | ALDH1A1GAAIKBKBPARP1CA1 | |
| SCHEMBL14154662 | 0.81 | ALDH1A1 (0.52) | ALDH1A1GAAIKBKBCA1CA2 | |
| SCHEMBL23088486 | 0.77 | CCR1 (0.47) | ALDH1A1GAAIKBKBPARP1CA1 | |
| SCHEMBL17596878 | 0.74 | MEN1 (0.46) | SMN1; SMN2NPC1LMNATSHRRAB9A | |
| SCHEMBL14553327 | 0.73 | ALDH1A1 (0.39) | ALDH1A1GAAIKBKBPARP1CA1 | |
| SCHEMBL17596865 | 0.73 | BACE1 (0.42) | ALDH1A1SMN1; SMN2NPC1LMNATSHR | |
| SCHEMBL12413878 | 0.71 | MEN1 (0.52) | ALDH1A1SMN1; SMN2NPC1LMNARAB9A | |
| SCHEMBL25367639 | 0.70 | MAOA (0.43) | ALDH1A1GAANPC1LMNATSHR | |
| SCHEMBL12412330 | 0.69 | ALDH1A1 (0.48) | ALDH1A1GAACA1CA2CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130011852-A1 | COMPOUNDS THAT INTERACT WITH KINASES | ALCHEMIA LIMITED (AU) | 2013-01-10 | — | — | US | disclosed |
| US-20080176815-A1 | Compounds that interact with kinases | ALCHEMIA LIMITED (AU) | 2008-07-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080176815-A1 | Compounds that interact with kinases | MAP3K6, MAP3K20, MAP4K2 | ALDH1A1 3275/4885GAA 2047/4885IKBKB 369/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.