Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 19/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1413920 | 1.00 | GHSR (0.40) | GHSRHDAC1HDAC6 | |
| SCHEMBL1414565 | 0.90 | GHSR (0.43) | GHSRHDAC1HDAC6 | |
| SCHEMBL4038449 | 0.77 | PIN1 (0.36) | — | |
| SCHEMBL4038445 | 0.77 | PIN1 (0.36) | — | |
| SCHEMBL1414241 | 0.77 | S1PR1 (0.37) | — | |
| SCHEMBL1414468 | 0.77 | S1PR1 (0.37) | — | |
| SCHEMBL1414469 | 0.77 | S1PR1 (0.37) | — | |
| SCHEMBL1414267 | 0.76 | GHSR (0.51) | GHSRHDAC1HDAC6 | |
| SCHEMBL1414271 | 0.76 | GHSR (0.51) | GHSRHDAC1HDAC6 | |
| SCHEMBL1414214 | 0.74 | GHSR (0.41) | GHSR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1966198-B1 | 2-AMINO-3,4-DIHYDRO-PYRIDO[3,4-D]PYRIMIDINE DERIVATIVES USEFUL AS INHIBITORS OF BETA-SECRETASE (BACE) | JANSSEN PHARMACEUTICA NV (BE) | 2011-03-16 | — | — | EP | disclosed |