Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.51 |
| ▸ | CA2 | P00918 | 2/20 | 0.51 |
| ▸ | ABL1 | P00519 | 1/20 | 0.45 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.45 |
| ▸ | SRC | P12931 | 1/20 | 0.45 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.45 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.45 |
| ▸ | SUV39H2 | Q9H5I1 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | STK17B | O94768 | 1/20 | 0.41 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12472530 | 0.85 | ABL1 (0.41) | CA1CA2ABL1PDGFRBSRC | |
| SCHEMBL8692897 | 0.84 | CA1 (0.66) | CA1CA2ABL1PDGFRBSRC | |
| SCHEMBL29491458 | 0.83 | NAMPT (0.51) | CA1 | |
| SCHEMBL392294 | 0.83 | NAMPT (0.51) | CA1 | |
| SCHEMBL14679151 | 0.79 | CA1 (0.60) | CA1CA2KDM4EPOLBTDP1 | |
| SCHEMBL3081630 | 0.79 | NAMPT (0.61) | CA1CA2POLBCYP3A4LMNA | |
| SCHEMBL4757472 | 0.78 | CA1 (0.59) | CA1CA2POLBUSP2LMNA | |
| SCHEMBL29391711 | 0.78 | CA1 (0.44) | CA1CA2ABL1PDGFRBSRC | |
| SCHEMBL937131 | 0.78 | CA1 (0.59) | CA1CA2ABL1PDGFRBSRC | |
| SCHEMBL6274441 | 0.78 | CA1 (0.58) | CA1CA2L3MBTL1CYP3A4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008083054-A2 | LIGANDS FOR CARDIAC BETA1 ADRENOCEPTOR FOR IMAGING CONGESTIVE HEART FAILURE | BRISTOL-MYERS SQUIBB PHARMA COMPANY (US) | 2008-07-10 | — | — | WO | disclosed |