Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT1 | Q99873 | 4/20 | 0.43 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.30 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.30 |
| ▸ | GSK3B | P49841 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8973334 | 0.80 | PRMT1 (0.59) | PRMT1MKNK1MKNK2GSK3B | |
| SCHEMBL8975508 | 0.74 | PRMT1 (0.71) | PRMT1MKNK1MKNK2 | |
| SCHEMBL2009167 | 0.71 | PRMT1 (0.57) | PRMT1MKNK1MKNK2GSK3B | |
| Hydrochloric Acid SCHEMBL2012811 | 0.69 | PRMT1 (0.55) | PRMT1MKNK1MKNK2 | |
| SCHEMBL3777290 | 0.67 | PRMT1 (0.53) | PRMT1MKNK1MKNK2 | |
| Hydrochloric Acid SCHEMBL3783268 | 0.66 | PRMT1 (0.51) | PRMT1MKNK1MKNK2 | |
| SCHEMBL8975569 | 0.66 | PRMT1 (0.63) | PRMT1 | |
| SCHEMBL14369775 | 0.65 | PRMT1 (0.50) | PRMT1MKNK1MKNK2 | |
| SCHEMBL30567466 | 0.64 | PRMT1 (0.49) | PRMT1 | |
| SCHEMBL8973340 | 0.64 | PRMT1 (0.56) | PRMT1MKNK1MKNK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1949896-A2 | Linear dicationic terphenyls and their aza analogues as antiparasitic agents | The University of North Carolina At Chapel Hill (US) | 2008-07-30 | — | — | EP | disclosed |