Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT1 | Q99873 | 4/20 | 0.53 |
| ▸ | NQO2 | P16083 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | PRF1 | P14222 | 1/20 | 0.44 |
| ▸ | APP | P05067 | 3/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.37 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.37 |
| ▸ | IKBKB | O14920 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3783268 | 0.98 | PRMT1 (0.51) | PRMT1NQO2KDM4EALDH1A1GAA | |
| SCHEMBL8973334 | 0.84 | PRMT1 (0.59) | PRMT1KDM4EALDH1A1MKNK1MKNK2 | |
| SCHEMBL13018325 | 0.81 | PRF1 (0.44) | PRMT1NQO2KDM4EALDH1A1GAA | |
| SCHEMBL8975508 | 0.77 | PRMT1 (0.71) | PRMT1NQO2ALDH1A1MKNK1MKNK2 | |
| SCHEMBL2009167 | 0.77 | PRMT1 (0.57) | PRMT1NQO2KDM4EALDH1A1MKNK1 | |
| Hydrochloric Acid SCHEMBL2012811 | 0.76 | PRMT1 (0.55) | PRMT1KDM4EALDH1A1MKNK1MKNK2 | |
| SCHEMBL3788601 | 0.72 | PRMT1 (0.58) | PRMT1NQO2ALDH1A1 | |
| SCHEMBL8975569 | 0.72 | PRMT1 (0.63) | PRMT1NQO2ALDH1A1 | |
| SCHEMBL1483888 | 0.71 | PRMT1 (0.46) | PRMT1KDM4E | |
| SCHEMBL28022519 | 0.71 | PRMT1 (0.46) | PRMT1ESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100331368-A1 | 2,5-DIARYL SELENOPHENE COMPOUNDS, AZA 2,5-DIARYL THIOPHENE COMPOUNDS, AND THEIR PRODRUGS AS ANTIPROTOZOAL AGENTS | UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL, THE | 2010-12-30 | — | — | US | claimed |
| WO-2009051796-A2 | 2,5-DIARYL SELENOPHENE COMPOUNDS, AZA 2,5-DIARYL THIOPHENE COMPOUNDS, AND THEIR PRODRUGS AS ANTIPROTOZOAL AGENTS | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2009-04-23 | — | — | WO | claimed |
| US-20100331368-A1 | 2,5-DIARYL SELENOPHENE COMPOUNDS, AZA 2,5-DIARYL THIOPHENE COMPOUNDS, AND THEIR PRODRUGS AS ANTIPROTOZOAL AGENTS | UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL, THE | 2010-12-30 | — | — | US | disclosed |
| WO-2009051796-A2 | 2,5-DIARYL SELENOPHENE COMPOUNDS, AZA 2,5-DIARYL THIOPHENE COMPOUNDS, AND THEIR PRODRUGS AS ANTIPROTOZOAL AGENTS | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2009-04-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100331368-A1 | 2,5-DIARYL SELENOPHENE COMPOUNDS, AZA 2,5-DIARYL THIOPHENE COMPOUNDS, AND THEIR PRODRUGS AS ANTIPROTOZOAL AGENTS | SELENOI, SCLY, GPX4 | PRMT1 788/4885NQO2 973/4885KDM4E 340/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.